Naloxone training Flashcards
Naloxone can be used for Opioid use disorder!!
Drug overdose is now the leading cause of death among Americans under 50 years old
____________:Decreased Receptor Sensitivity to Opioids Over Time;Repeated exposure to opioids (for any reason)
desensitizes opioid receptors and results in
down- regulation;
It will now take more opioid to cause the same effect
Tolerance
___________________:When opioid receptors are not exposed to
opioids for any period of time, the receptors
return to baseline. **It will now take less opioid to cause the same
effect.If the same amount of opioid is given, it will
cause a stronger reaction which cause an overdose
Decreased Tolerance
If someone hasn’t used opioids used for a while and they have been on rehabilitation and they have been in the prison system or weren’t able to get medication or the drug then they had decreased tolerance they need to use less if they are going back to using
__________________ is when the body requires a specific dose of a drug in
order to prevent withdrawal symptoms.
Physical
dependence
Physical Dependence does NOT equal addiction!
Withdrawal is painful for a patient and creates a huge to keep using because withdrawal is painful for a patient
How do people move from use of prescription opioids to
heroin? ___________________
afraid of going into withdrawal
What percent of people are at risk for developing an OUD with
exposure to opioids? 3% to 19% develop opioid use disorder
People misusing prescription opioids might try to switch from prescription opioids to heroin because its easier to get and this indicates the disease is getting more dangerous
about 45% of people who use heroin started with misuse of prescription opioids some people just develop opioid use disorder by just starting heroin…there is no one set path
___________is a chronic and reoccurring condition characterized by a change in
the structure and function of the brain
Severe OUD
The evidence-based treatment of OUD is multifaceted and often includes pharmaceutical treatment, such as methadone, buprenorphine, or naltrexone
You can’t use naloxone on yourself so someone would have to use it because your unconsciousness
An _____________ occurs when a toxic amount of a drug or a toxic combination of drugs overwhelms the body.
overdose
Opioid overdose is characterized by inadequate _________(respiratory depression) and loss of _____________.
This leads to a lack of oxygen in the body which will lead to
death if no intervention is made
inaqeuate breathing and loss of consciousness
Overdose can happen with Rx opioids or unregulated substances
The amount of drug needed to cause a breathing emergency is different from person to person!
Overdose Risk Factors
There is an increased likelihood of overdose when any of the
following factors are present:
Decreased tolerance due __________
incarceration
detox
Prior nonfatal overdose
_____________ opioid prescription
Long-acting formulations
Using unregulated substances alone
abstinence
high dose
Neurobiology of Addiction
Reward centers and mechanisms in the brain
Substances or activities that release dopamine in the
nucleus accumbens have been clearly linked to disordered
use
Downstream effects of euphoria and pleasure
Conditions the person to associate using the substance with
the euphoric and pleasurable sensations
Opioid use disorder (OUD) is a _______ often _________
condition
Viewing OUD as a medical condition and providing
medications for the treatment of OUD, education, and
support have been shown to decrease the risk of accidental
overdose or relapse into opioid use
chronic
relapsing
Narcan is difficult to get access in rural settings
