Wed - Dirty D - cell mediated cytotoxicity Flashcards

1
Q

CD28

A

on t cells. gets activated when touched by CD80/86 on CPC

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2
Q

what receptors activate NK cells and what inhibit

A

lectin like receptors activate (CD94 + NKG2) - EXCEPT FOR CD94-NKG2A which inhibits and trumps all

Immunoglobulin like receptors inhibit

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3
Q

What releases perforin? granzyme?

A

Perforin release by NK cells and eosinophils.

Granzyme release by NK cells

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