Wed - Dirty D - cell mediated cytotoxicity Flashcards
1
Q
CD28
A
on t cells. gets activated when touched by CD80/86 on CPC
2
Q
what receptors activate NK cells and what inhibit
A
lectin like receptors activate (CD94 + NKG2) - EXCEPT FOR CD94-NKG2A which inhibits and trumps all
Immunoglobulin like receptors inhibit
3
Q
What releases perforin? granzyme?
A
Perforin release by NK cells and eosinophils.
Granzyme release by NK cells