Water and Lipid soluble hormones

Question 1

Describe a lipid soluble hormones

Answer 1

They are hydrophobic 
They use a transport protein 
There receptors are located inside the cell 
It is a direct action 
Examples include T3 and T4

Question 2

Describe the process of a lipid soluble hormones

Answer 2

• Diffuses from the blood stream into the cell
• Activates the receptor hormone
• Forms new mRNa
• Directs synthesis of specific protein
• New protein alter the cells activity

Question 3

Describe a water-soluble hormone

Answer 3

Is hydrophobic 
Transports freely in blood 
Receptor is located at plasma membrane 
Is an indirect process (second messenger)
Examples include serotonin and melatonin

Question 4

Describe the process of a water soluble hormone

Answer 4

Binds hormone (first messenger) activates G protein
Activates adenylate cyclase
Activated adenylate cyclase converts ATP to cAMP
cAMP second messenger activates protein kinases (enzymes that modify other proteins)
Protein kinases phosphorylate cellular proteins
Millions cause reactions cause physiological response