Hormones Flashcards
What peptides and proteins does the Posterior pituitary secrete
Oxytocin (OT) Antidiuretic hormone (ADH)
What peptides and proteins does the anterior pituitary secrete
Human growth hormone (hGH) - Thyroid stimulating hormone (TSH) Follicle-stimulating hormone (FSH) Luteinising hormone (LH) Prolactin (PRL) Adrenocorticotropic hormone (ACTH) Melanocyte-stimulating hormone (MSH)
Describe the principal action of Human growth hormone (hGH)
Stimulates liver (and other tissues) to synthesis and secrete insulin like growth factors Promotes growth of body cells, protein synthesis, tissue repair, lipolysis and elevation of blood glucose concentration
Describe the principal action of Thyroid stimulating hormone (TSH)
Stimulates synthesis and secretion of thyroid hormones by thyroid gland
Describe the principal action of Follicle-stimulating hormone (FSH)
In females, initiates development of oocytes and induces ovarian secretion of oestrogens
In males stimulates testes to produce sperm
Describe the principal action of Luteinising hormone (LH)
Females: stimulates secretion of oestrogens and progesterone, ovulation and formation of corpus luteum
Males: stimulates testes to produce testosterone
Describe the principal action of Prolactin (PRL)
Promotes milk production by mammary glands
Describe the principal action of Adrenocorticotropic hormone (ACTH)
Stimulates secretion of glucocorticoids (cortisol) by adrenal cortex
Describe the principal action of Melanocyte-stimulating hormone (MSH)
Unknown role in humans may influence brain activity (cause darkening of skin)
Describe the principal action of oxytocin (OT)
Stimulates contraction of smooth muscle cells of uterus during childbirth
Stimulates contraction of myoepithelial cells in mammary glands to cause milk ejection
Describe the principal actions of Antidiuretic hormone (ADH)
Conserves body water by decreasing urine volume
Decreases water lose
Raises blood pressure by constricting arterioles
What makes up the anterior pituitary, describe
Epithelial tissue
Regulated by neurosecretory cells and negative feedback
What makes up the posterior pituitary, describe
Neural tissue
Does not synthesise hormones it does store and release two hormones
Consists of axons and axon terminals
What are the actions of thyroid hormones
- Increase basal metabolic rate (rate of oxygen consumption)
- Stimulates synthesis of sodium-potassium pumps
- Regulates metabolism
- Enhances actions of catecholamines
- Accelerate body growth
How is thyroid hormone secretion controlled
- Low blood levels of T3 and T4 stimulates hypothalamus to secrete TRH
- TRH enters the hypophyseal portal veins flow to the anterior pituitary where it stimulates Thyrotrophs to secrete TSH
- TSH stimulates all aspects of thyroid follicular cell activity
- Thyroid follicular cells are released until normal
- An elevated number of T3 inhibits release of TRH and TSH (negative feedback)