Warts and Molluscum

Question 1

describe clinical features of verruca vulgaris

Answer 1

hyperkeratotic, exophytic, dome papules or nodules

most common on fingers, dorsal hands

punctate black dots are thrombosed capillaries, can koebnerize (spread w/ trauma)

Question 2

etiologies of warts

Answer 2

HPV viruses:

verruca vulgaris
verrucae planae- flat warts
palmoplantar warts
condylomata acuminata: external genital warts

Question 3

transmission/infection w/ HPV

Answer 3

spread skin to skin, surfaces

infects basal keratinocytes of cutaneous and mucosal epithelium

Question 4

describe verrucae planae

Answer 4

skin colored or pink

smooth surfaced and slightly elevated, flat topped

Question 5

pres of palmoplantar verruca

Answer 5

thick endophytic papules, central depression

can be painful

Question 6

tx for warts

Answer 6

most resolve in 1-2 yrs

most tx are destructive or stimulate immune response- cryotherapy or salicylic acid w/ removal of dead skin

Question 7

side effects of cryotherapy

Answer 7

hyperpigmentation (or hypo in darker skin) ring wart, scar, blister

Question 8

clinical features of genital warts

Answer 8

sessile exophytic papules

can be broad or large conflent plaques

Question 9

HPV types associated w/ genital warts and neoplasia

Answer 9

6,11- genital warts

16,18- neoplasia

gardasil vaccine protects against these

Question 10

imiquimod moa

Answer 10

TLR 7 and 8 agonist stimulates immune response

Question 11

clinical features of molluscum

Answer 11

flesh colored to translucent, dome shaped papules, some w/ umbilication

usually trunk, face, extremities, genitals

Question 12

etiology of molluscum

Answer 12

benign asymptomatic poxvirus infection

Question 13

tx for molluscum

Answer 13

usually resolves w/i mos

cryotherapy, curettage, cantharidin (blister beetle extract)

imiquimod and topical retinoids