Urticaria

Question 1

define urticaria

Answer 1

aka hives

vascular rxn of skin w/ wheals surrounded by blanchable red halo or flare

cardinal sx is pruritis or itch

Question 2

etiology of urticaria

Answer 2

type 1 hypersensitivity, swelling of upper dermis

papules/plaques last less than 12 hrs, may come up somewhere else

Question 3

meaning of spongy, edema changes

Answer 3

deeper down in the skin

Question 4

common causes of acute uriticaria

Answer 4

idopathic
post infection
food rxns
drugs or infusions

usually not detergents or contact allergens, except latex

Question 5

etiology of chronic urticaria

Answer 5

usually idopathic

physical- pressure, heat, water, etc (maybe emotion)

chronic autoimmune- IgE receptor Abs

Question 6

most common physical form of urticaria

Answer 6

dermatographism- localized edema or wheal w/i seconds

Question 7

effector cell of urticaria

Answer 7

mast cell

Question 8

immunologic vs non uriticaria

Answer 8

immunologic- antigen binds IgE on mast cell causing histamine release

non- direct mast cell degranulation w/o antigen

Question 9

tx of urticaria

Answer 9

antihistamines- oral H1 are first line for acute and chronic

2nd generation less sedating

Question 10

angiodema def

Answer 10

same pathogenesis of urticaria, but deep dermis w/ subq swelling

Question 11

location for angioedema

Answer 11

face or an extremity- maybe tongue, pharynx, larynx, bowels

maybe painful but not pruritic

Question 12

more serious condition assoc w/ urticaria and angioedema

Answer 12

anaphylaxis- need to ask about SOB, throat tightness, nausea, vom, abdominal pain

assess ABCs

Question 13

tx for anaphylaxis

Answer 13

epi, IV fluids, oxygen