Warfarin Flashcards

1
Q

When should a patient maintain a warfarin INR of 2.5

A
  • VTE
  • AF
  • Cardioversion
  • Myocardial Infarction
  • Cardiomyopathy
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2
Q

What are the 4 indications of Warfarin

A
  • venous thrombosis
  • pulmonary embolism
  • atrial fibrillation
  • ischemic attacks
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3
Q

When should a patient maintain a warfarin INR of 3.5

A
  • Recurrent VTE
  • Has mechanical heart valves
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4
Q

Warfarin Side effects

A
  • Skin necrosis and calciphylaxis (rash)
  • Haemorrhage
  • Teratogenic
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5
Q

Specifically which trimesters should you avoid using Warfarin

A

1st
3rd

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6
Q

What foods should you avoid while on Warfarin

A

Vitamin K rich foods
- green leafy vegetables
(reduces efficacy as contains antidote)

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7
Q

Which juices should you avoid when taking Warfarin

A
  • Pomegranate
  • Cranberry
  • Graefruit
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8
Q

What are Warfarin Interactions

A
  • Miconazole (Darktarin/Dactacort)
  • CYP450 Inducers
  • CYP450 Inhibitors
  • Tamoxifen
  • NSAIDs
  • tramadol
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9
Q

What 5 monitoring criteria must be met before commencing Warfarin

A
  • full blood count
  • LFT
  • Renal function
  • BP
  • Thyroid function tests
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