Warfarin Flashcards
1
Q
When should a patient maintain a warfarin INR of 2.5
A
- VTE
- AF
- Cardioversion
- Myocardial Infarction
- Cardiomyopathy
2
Q
What are the 4 indications of Warfarin
A
- venous thrombosis
- pulmonary embolism
- atrial fibrillation
- ischemic attacks
3
Q
When should a patient maintain a warfarin INR of 3.5
A
- Recurrent VTE
- Has mechanical heart valves
4
Q
Warfarin Side effects
A
- Skin necrosis and calciphylaxis (rash)
- Haemorrhage
- Teratogenic
5
Q
Specifically which trimesters should you avoid using Warfarin
A
1st
3rd
6
Q
What foods should you avoid while on Warfarin
A
Vitamin K rich foods
- green leafy vegetables
(reduces efficacy as contains antidote)
7
Q
Which juices should you avoid when taking Warfarin
A
- Pomegranate
- Cranberry
- Graefruit
8
Q
What are Warfarin Interactions
A
- Miconazole (Darktarin/Dactacort)
- CYP450 Inducers
- CYP450 Inhibitors
- Tamoxifen
- NSAIDs
- tramadol
9
Q
What 5 monitoring criteria must be met before commencing Warfarin
A
- full blood count
- LFT
- Renal function
- BP
- Thyroid function tests