Amiodarone and Digoxine Part 2 Flashcards
1
Q
What is the dose of Digoxin for Heart Failure
A
62.5 to 125 mcg
2
Q
What is the dose of Digoxin for Atrial Fibrillation
A
125 to 200mcg OD
3
Q
What is the serum therapeutic range of Digoxin
A
0.7 to 2 ng/ml
4
Q
At which serum level is Digoxin toxic
A
> 1.5 to 3 ng/ml
5
Q
What monitoring is required for Digoxin
A
- serum electrolytes
- renal function
6
Q
Digoxin Interactions
A
- BB
- TCA (induce arrhythmias)
- Hypokalemic drugs
- CYP450 Inducers
- CYP450 Inhibitors
7
Q
What to do if signs of Digoxin toxicity occur
A
Stop immediately
8
Q
What is the antidote to Digoxin
A
Digoxin Specific Antibody Fragments (DIGIFab)
9
Q
If also taking an oral antacid, how should you space out Digoxin dosing
A
Separate does of each by 2 hours
10
Q
If switching from IV to Oral Digoxin what should you do
A
increase dose by 20 to 33%
