Stroke and Hyperlipidaemia Part 2

Question 1

What 2 statins can be taken any time of day

Answer 1

• Atorvastatin
• Rosuvastatin

Question 2

What condition should be managed before starting a statin

Answer 2

Hypothyroidism

Question 3

What needs to be checked before starting a statin and why

Answer 3

patients at hight risk of diabetes need to have fasting blood glucose checked (repeat after 3 months)

Question 4

What monitoring needs to take place when starting a statin

Answer 4

• Thyroid function
• Renal function
• Lipid Profile
• Liver Function
• Creatinine Kinase

Question 5

Side effects of Statins

Answer 5

• Rnhabdomylosis
• Interstitial lung disease
• Teratogenic

Question 6

How long before conceiving should statins be stopped

Answer 6

3 months before

Question 7

Statin Interactions

Answer 7

• CYP450 Inducers and Inhibitors
• Grapefruit Juice
• Macrolides
• Fuscidic Acid

Question 8

What happens if someone is on a statin and they get a prescription for a macrolide or fuscidic acid

Answer 8

stop taking the statin for the duration of the treatment

(in case of fuscidic acid, also for 7 days after)

Question 9

What is the interaction of Statins and Ezetimibe/fibrates

Answer 9

increase risk of Rnhabdomylosis / muscle side effects

Question 10

Examples of Fibrates

Answer 10

• Benzafibrate
• Fenofibrate