Hypertension and Anti-Hypertenisve Drugs

Question 1

What is stage 1 Hypertension

Answer 1

140/90 to 159/99 (normal)

135/85 to 149/94 (ambulatory)

Question 2

What is stage 2 Hypertension

Answer 2

160/80 to 180/120 (normal)

> 150/95 (ambulatory)

Question 3

What is stage 3 Hypertension

Answer 3

> 180/120

Question 4

When should you offer pharmacological treatment

Answer 4

Stage 1 and…
- < 80years with kidney disease
- < 60years with QRISK 10
- >80 with BP over 150/90

Question 5

1st and 2nd Line for Hypertension in <55 years or Type 2 diabetes

Answer 5

1st Line:
- ACEi / ARB

2nd Line:
- ACEi / ARB + CCB / Thiazide

Question 6

1st and 2nd Line for Hypertension in >55 years or Afro-Caribbean

Answer 6

1st Line:
CCB

2nd Line:
CCB + ACEi / ARB / Thiazide

Question 7

3rd Line Hypertension for all patients

Answer 7

3rd Line:
Triple Therapy
ACEi / ARB + CCB + Thiazide

Question 8

4th Line Hypertension for all patients

Answer 8

If serum Potassium is >4.5
ADD: BB or Alpha Blocker

If serum Potassium is <4.5
ADD: Spironolactone

Question 9

ACEi / ARB Side effects

Answer 9

• Cough (ACEi only)
• Angioedema (ACEi only)
• Hyperkalemia
• Renal Failure
• Hepatic Failure
• Dizziness

Question 10

What drugs interact with ACEi / ARB to cause renal failure

Answer 10

• Potassium Sparing Diuretics
• NSAIDs

Question 11

What drugs interact with ACEi / ARB to increase hyperkalaemia

Answer 11

• Potassium Sparing Diuretics
• NSAIDs
• Heparins
• Beta Blockers