W9/L7: Lung disease

Question 1

What are some examples of obstructive lung diseases?

Answer 1

Asthma
COPD
Bronchiectasis

Question 2

What are some examples of restrictive lung disease?

Answer 2

Idiopathic pulmonary fibrosis
Pneumoconiosis
Sarciodosis
Honey-comb lung

Question 3

Define asthma

Answer 3

Increases airway responsiveness to various stimuli leading to episodic bronchoconstriction which is at least partially reversible.

Question 4

What do you see in the serum of people with atopic asthma?

Answer 4

Increased serum IgE

Question 5

What are the short-term complications of asthma?

Answer 5

Death
Atelectasis
Spontaneous pneumothorax

Question 6

What are some long-term complications of asthma?

Answer 6

Airway remodelling

Chronic hypoxia -> pulmonary hypertension -> cor pulmonale

Question 7

Define atelectasis

Answer 7

Collapse of the lung

Question 8

Define emphysema

Answer 8

Abnormal, permanent enlargement of air spaces distal to the terminal bronchiole

Question 9

What is the (broad) cause of emphysema?

Answer 9

Destruction of the alveolar wall without fibrosis

Question 10

What are some complications of emphysema?

Answer 10

Pneumothorax

Hypoxia -> pulmonay hypertension -> cor pulmonale

Question 11

Define chronic bronchitis:

Answer 11

A clinical definition: a persistent cough productive of sputum for at least 3/12 in 2 consecutive years, without any other cause