W8/L8: Viruses 2

Question 1

What is the receptor for influenza attachment?

Answer 1

Sialic acid

Question 2

What are the two ways in which an enveloped virus can become intracellular?

Answer 2

Membrane fusion

Endocytosis

Question 3

What’s an example of a virus that enters the cell via membrane fusion?

Answer 3

HIV

Question 4

What’s an example of a virus that enters the cell via endocytosis?

Answer 4

Togavirus

Question 5

In ways can a virus exit the endosome it’s found itself in?

Answer 5

Lysis of the endosome

The pH of the endosome induces a conformational change in the viral proteins that exposes a fusion region.

Question 6

In general, where in the cell do DNA viruses replicate?

Answer 6

Nucleus

Question 7

In general, where in the cell do RNA viruses replicate?

Answer 7

Cytoplasm

Question 8

What’s an example of an RNA virus that doesn’t replicate in the cytoplasm?

Answer 8

Influenza

Question 9

What is the capsid symmetry of all non-enveloped viruses?

Answer 9

Icosahedral