W5 - Pancreas Flashcards
Pancreas is a heterocrine organ, what does this mean?
It is partially exocrine and partially endocrine
99% of the pancreas is exocrine, what is the general function/molecule produced?
Enzymes for digestion of proteins, lipids, carbs and nuc acids
1% of the pancreas is endocrine, what is the general function/molecule produced?
Functions to regulate blood glucose levels
Acinar cells are organised into ??? to produce pancreatic juices
Acini, clusters of cells surrounding ducts
Enzymes in pancreatic juices don’t damage the internal surface of the GI tract, how?
THey’re secreted as proenzymes so they arent necessary until cleaved
Lumen of acini –> intercalated duct –> ??? –> ???
Intralobular duct, interlobular duct
Islets of Langerhans are found in higher proportions of the tail than anywhere else in the pancreas, what do they produce?
Alpha - glucagon, beta - insulin, delta - somatostatin
Where do the pancreatic juices enter the small intestine?
Duodenum