W5 - Liver Flashcards
What two vessels carry blood into the liver?
Portal vein and hepatic artery
What vessel carries blood away from the liver back to the heart?
Hepatic vein
What 3 things does the liver metabolise?
Fat, carbohydrates and proteins
What 3 things can be stored in the liver?
Glycogen, vitamins and iron
What is synthesised and secreted in the liver?
Bile
What does it mean that the liver undergoes the intermediary metabolism?
It detoxifies various drugs and toxins e.g. alcohol
The liver is made up of lots of repeating structures called…
Lobules
What is the smallest functional part of the liver?
Sinusoid
What do all hepatocytes produce?
Bile
Describe the pathway of the blood in a hepatic lobule
FRom portal vein and hepatic artery , through the portal tract, to the central hepatic vein
What cell type are sinusoids lined with?
FEnestrated endothelial cells
Bile is secreted from hepatocytes into grooves in plasma membranes (bile canaliculi), what do these fuse to form?
Canals of Hering
What does bile aid in?
Lipid digestion in the small intestine
Bile canaliculi –> canals of hering –> bile ductules –> bile ducts –> ??? –> ??? –> ??? –> ???
Common hepatic duct, common bile duct, ampulla of vater and finally duodenum
There’s an oxygen gradient in the sinusoids, is it highest closest to the portal tract or to the hepatic vein?
Nearest the portal triad
