W32/L8 Flashcards

1
Q

What is the common presentation of gonorrhoea in men?

A

Purulent & profuse urethral discharge

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2
Q

In which sites is gonorrhoea often asymptomatic?

A

Rectum
Pharynx
Cervix

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3
Q

What are some reasons that gonorrhoea has higher rates in indigenous communities?

A

Poor/slower access to testing & treatment = longer duration of infection

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4
Q

What symbol means the “basic reproductive rate”

A

R0

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5
Q

What does the basic reproductive rate mean?

A

The number of cases of an infection that will arise from a primary case

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6
Q

What values of R0 will cause an epidemic

A

R0 > 1

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7
Q

For which values of R0 will a disease die out?

A

R0 < 1

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8
Q

Why does prevalence of an infection level off, even when R0 is greater than 1?

A

As the prevalence of the disease increases, the number of susceptible people decreases

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9
Q

R0 =

A

Beta * c * D

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10
Q

What is Rt?

A

The effective reproduction rate

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11
Q

Rt =

A

Beta * c * D * x

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12
Q

What is “beta” in the reproductive rate expression?

A

Transmission probability per partnership

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13
Q

What is “c” in the reproductive rate expression?

A

Rate of partner change

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14
Q

What is “D” in the reproductive rate expression?

A

Duration of infection

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15
Q

What’s “x” in the reproductive expression?

A

The proportion of the population who are susceptible

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16
Q

What things will influence beta for an STI?

A
Condom use
Types of sex
Duration of sex
Presence of other STIs
How infectious their disease is currently (1" infections, high viral load etc)

Duration of partnership

17
Q

What things will influence D for an STI?

A

Presence of symptoms

Access to screening & t’ment

18
Q

What component of the reproductive rate is most straightforward to target as a pop health measure?

A

D - duration of infectiousness

19
Q

What does assortative mixing refer to?

A

High risk people having sex with other high risk people

20
Q

What does disassortative mixing refer to?

A

High risk people having sex with low risk people

21
Q

What type of mixing is bad for population control of an infection

A

Assortative mixing

22
Q

What does concurrency refer to?

A

Simultaneous partners

23
Q

Even if the number of partners per year is the same, why is concurrency worse than serial monogamy for population control of infections?

A

There are more partners during a persons duration of infection

(And they presumably have multiple partners too)

24
Q

What does the core group refer to in epidemiology?

A

The small portion of a population who have many partners