W31/L1: STIs

Question 1

What are the 4 broad ways that STIs usually present?

Answer 1

Discharge
Genital lesion
Dermatological abnormality
PID

Question 2

What is the typical presentation of gonorrhoea?

Answer 2

Thick, creamy urethral discharge

Question 3

What’s the cell morphology of gonorrhoea?

Answer 3

Gram -‘ve diplococci

Question 4

What proportion of infected females are asymptomatic?

Answer 4

80%

Question 5

What proportion of infected men are asymptomatic?

Answer 5

10%

Question 6

What type of human cell does gonorrhoea like to adhere to?

Answer 6

Columnar epithelium

Question 7

What does perinatal infection with gonorrhoea usually present as?

Answer 7

Opthalmia / conjunctivitis

Question 8

What’s the selective media for growth of gonorrhoea?

Answer 8

Thayer-Martin agar

Question 9

What is standard treatment for gonorrhoea?

Answer 9

Ceftriaxone + azithromycin

Question 10

Why do we use ceftriaxone + azithromycin in gonorrhoea t’ment?

Answer 10

The ceftriaxone works on the cell wall, and azithromycin works on ribosomes, so they’re synergistic

Also azithromycin is effective against chlamydia, which is often present as a co-infection

Question 11

Which is the most common STI?

Answer 11

Chlamydia

Question 12

What two forms can chlamydia exist in?

Answer 12

Elementary bodies

Reticulate bodies

Question 13

What’s the infectious form of chlamydia?

Answer 13

Elementary bodies

Question 14

What’s the replicating form of chlamydia?

Answer 14

Reticulate bodies

Question 15

What are the common male presentations of chalmydia?

Answer 15

Dysuria
Meatal erythema
Clear urethral discharge

Question 16

What sort of discharge does trichomonas vaginalis usually cause?

Answer 16

Frothy, green-yellow vaginal discharge