W30 Pharmacology and therapeutics of common drugs in the treatment of liver disease Flashcards

1
Q

Alcoholic liver disease (Acute)
What are the treatments?

Use electronic medicines compendium OR drug bank online to identify the PK and PD mode of action for each drug listed within this lecture

A

Benzodiazepines:
* Diazepam
* Chlordiazepoxide- used to treat the withdrawal symptoms of acute alcoholism
Seizures:
* Lorazepam/Diazepam

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2
Q

Treatment of ALD Complications:
Ascites?
Portal Vein HTN?
Varicies?
Encephalopathy?
Bleeding?
Sponateous bacterial peritonitis? (SBP)
Non-alcoholic fatty liver?

A
  • Spironolactone (diuretic), Tazocin
  • Propanalol, Carvedilol, Beta blockers (unlicensed indication)
  • Terlipresin
  • Thiamine, Pabrinex, Lactulose, Rifaxamin
  • Vitamin K
  • Abx (Co-trimoxazole or Ciprofloxacin)
  • Lifestyle changes

Use electronic medicines compendium OR drug bank online to identify the PK and PD mode of action for each drug listed within this lecture

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