W3 GI tract Flashcards

1
Q

where does the stoamach join the oesophagus

A

at the gastroesophageal junction

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2
Q

what is the most proximal part of the stomach

A

cardia

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3
Q

what is the roof of the stomach

A

fundus

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4
Q

what are the 2 most distal part of the stomach

A

pylorus and antrum

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5
Q

what are the folds of the stomach called

A

rugae

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6
Q

what are the 4 layers of the stomach

A

mucsosa
submucsosa
muscularis externa
serosa

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7
Q

what is the mucsosa

A

outer surface with epithelium

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8
Q

what is the submucsosa

A

connective tissue and blood/lympth vessels

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9
Q

what is the muscularis externa

A

3 layers of smooth muscle fibres

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10
Q

what is the serosa

A

a membrane on the outside the stomach

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11
Q

what is the serosa of the small intestine called

A

mesothelium

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12
Q

what are peyer patches in small intestine

A

immune follicles in the submucosa of the distal ileum

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13
Q

how is the oesophagus lined

A

squamous

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14
Q

which layer sits under the epithelial layer of oesophagus

A

lamina propria

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15
Q

where does the majority of proliferation occur

A

basal layer

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16
Q

what is the sub mucosa

A

small mucus secreting glands

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17
Q

are gland bases columnar or squamos

A

columnar

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18
Q

when does the mucosa change into a glandular secretory

A

at the junction of oesophagus and stomach

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19
Q

what do gastric cardia produce

A

mucus + lysozyme

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20
Q

what muscin do foveolar cells secrete

A

muc5ac

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21
Q

what mucins do mucous secreting cells secrte

A

muc6

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22
Q

what is secreted in fundus mucosa

A

acid and pepsin

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23
Q

what are foveolar cells also known as

24
Q

where are stem cells found in gastric glands

A

isthmus and neck of stomach

25
how are mucous neck cells found as
clusters in neck of gastric glands
26
what do mucous neck cells secrete
trefoil factor 2
27
which cells produce hydrochloric acid
parietal cells
28
where are parietal cells found
upper half of gastric glands
29
what is a main feature of parietal cells
large amounts of mitochondria
30
what do chief cells secrete
pepsinogen
31
what is pepsinogen converted to
pepsin
32
what type of enzyme is pepsin
proteolytic enzyme
33
which cells secrete hormones
neurodendocrine cells
34
what does gastrin do (g cell)
activate parietal cells
35
what does somatostatin (D cell) do
inhibits release of gastrin
36
what are enterocytes
absorptive epithelial cells
37
what do glycocalyx do
produce acidic mucopolysaccharides and glycoproteins
38
what do goblet cells do
secrete mucins like muc2 mostly found in crypt
39
what are paneth cells
densely packed granules that produce lysozymes
40
what are APUD cells
types pf endocrine cell types
41
what stain is used for neuroendocrine cells
chromogranin A
42
what does brunners gland do
produces alkaline mucus to neutralise stomach acid
43
how is brunner gland described as
compound tubular mucous glands
44
where is brunners gland found
submucosa of duodenum
45
what are 3 diff between duodenum and rest of small GI
has brunners glands longer villi more goblet cells
46
where are the majority of peyer patches found
ileum
47
what is the muscularis propria layer described ss
longitudinal and circular
48
where does the large intestine join the ileum of small intestine
ileocaecal junction
49
what is the appendix
tubular sac attached to caecum part of intestine contain lymphoid tissue
50
what does the colon do in the large intestine
thick muscular wall for the recovery of water absorption and mucus secreting cells
51
what type of epithelium is the anal canal
stratified squamous
52
what is rue skeletal muscle around the anal canal
anal sphincter
53
what is the rectum
distal part of large bowel
54
which cell type is more commonly found in the rectal mucosa
goblet cells
55
what is the meissner plexus
network of unmyelinated nerves part of peripheral nervous system
56
what is auerbach plexus
regulation of contractions between circular and longitudinal layers of muscle