W2 Epithelia Flashcards

1
Q

what do mature fibroblasts look like

A

dense and very pink collagen fibres with elongated nuclei

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2
Q

whats the job of mature fibroblasts

A

maintain integrity of tissue by slow turnover of EM

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3
Q

how would you observe that more strength is needed ina tissue

A

more dense pink collagen

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4
Q

what are basement membranes

A

arrangement of EM proteins between support tissue and parenchymal

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5
Q

whats the basement membrane between nerve and muscle tissue

A

external lamina

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6
Q

what do basement membrane do

A

control epithelial growth

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7
Q

what type of collagen are basement membrane made of

A

type 4

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8
Q

what are the 3 layers of basement membrane

A

lamina lucida
lamina densa
lamia fibroreticularis

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9
Q

what is the lamina lucida

A

transparent layer abut the plasma membrane of basal cells connected

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10
Q

what is lamina densa

A

intermediate e- dense layer

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11
Q

what is the lamina reticularis

A

broad layer which merges with supporting tissues

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12
Q

what type of collagen is lamina reticularis made of

A

type 3 and fibronectin

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13
Q

what type of collagen is lucida and densa made of

A

type 4 collagen + laminin

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14
Q

what are adipose tissue

A

store fat in clumps with rich blood supply

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15
Q

what are the 3 layers of skin

A

epidermis
hypodermis
dermis

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16
Q

what is the hypodermis made of

A

mature adipose tissue

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17
Q

what is the dermis made of

A

bundles of collagen fibres and elastic fibres

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18
Q

what are the 2 layers of the dermis

A

reticular + papillary

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19
Q

what are white adipose tissue

A

20/25% of male/female body weight of mostly lipid

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20
Q

whats the role of white adipose tissue

A

thermal insulator

21
Q

what is stratum basale

A

basal layer of keratinocytes that proliferates continuously

22
Q

what is the role of breon adipose tissue

A

temperature regulation

23
Q

where is type 1 collagen found

A

dermis bone and fibrous supporting tissue

24
Q

where are type 2 collagen found

A

hyaline cartilage

25
what is the stratum spinosum called
the prickle layer, keratinocytes held by desmosomes
26
what is the stratum granulosum made of
basophilic cytoplasmic ganules
27
what is collagen and its job
fibre which provides tensile strength
28
what is collagen made of
tropocollagen
29
what is the stratum corneum
keratin plates attached to the edge
30
what are supporting tissues made of
specialised cells EM made of ground substance and fibres
31
how do ground substances appear
pale and unstained
32
what colour are fibrous proteins stained
pink bundles
33
what are the 4 cells of epidermis
keratinocytes langerhans cells melanocytes merkel cells
34
what do keratinocytes do
create keratin layer
35
what are the origins of supporting tissues
mesodermal tissue
36
where are melanoncytes mostly found
basal layer
37
what do langerhans cells do
antigen presentation
38
what are hair follicles normally associated to
M and G
39
what are sebaceous glands
secrete sebum (oil)
40
what are the mechansim of holocrine secretion
release whole cells of sebum
41
what are eccrine sweat glands/duct
out layer of myocytes
42
what are the functions of the skin
protection moisture control metabolic processes thermoregulation sensory
43
whats the function of the hypodermis
protection amd insulation lipid storage thermoregulation
44
what do all epithelia contain
cytokeratin intermediate filaments
45
what is type 3 collagen
reticulum
46
what are type 7 collagen
anchoring fibirls to basement membrane
47
what are type 4 collagen
form a mesh like structure in basement membranes
48
how do you stain type 3 collagen and its positive result
using metallic silver -> stained black