W3 amino acids + proteins + lipids Flashcards

1
Q

how many amino acids are there

A

20

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2
Q

where is there electrostatic interactions

A

between cation bases and pi

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3
Q

where do H bonds form during secondary protein structure

A

between C=O and N-H groups

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4
Q

how far apart are C=O and N-H group interactions

A

4 amino acids apart

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5
Q

what are beta sheets normally depicted as

A

flat arrows

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6
Q

how are tertiary structure proteins stabilised

A

H bonds + VDWs
weak aromatic stacking

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7
Q

where are the interactions of quaternary structure proteins

A

intermolecular

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8
Q

what happens when EV6 changes

A

sickle cell anemia

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9
Q

what happens when a protein is phosphorylated

A

becomes more negative and hydrophilic

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10
Q

what are the 4 common salt bridges

A

1) Glutamate + Lysine
2) Glutamate + Asparagine
3) Aspartate + Lysine
4) Aspartate + Asparagine

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11
Q

where do you get omega 6 and 3 FA from

A

diet

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12
Q

what are the steps to fatty acid synthase

A
  • acyl carrier protein joins acetate with malonate
  • done by ketosynthase and removes CO2
  • 4 C ketoacyl goes through ketoreduction + dehydration + enoyl reduction
  • makes a 4 chain saturated FA
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13
Q

what is the role of desaturase

A

convert saturated FA to unsaturated FA

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14
Q

which FA has double bonds

A

unsaturated FA

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15
Q

what is the importance of EFA

A

maintain cell membrane
inflammatory responses

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16
Q

what is the methyl end of the FA called

A

omega end

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17
Q

what is the carboxyl end of the FA called

A

delta

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18
Q

how many more times is triglyceride more effective than glycogen

A

6 times

19
Q

what are the 3 classes of membrane lipids

A

glycerophospholipids
sphingolipids
cholesterol

20
Q

what does amphiphilicity mean

A

both hydrophobic and hydrophilic

21
Q

what shape do lipids form

A

cylinders

22
Q

what shape do fatty acids form

A

cones

23
Q

what is the process of glucose to pyruvate called

A

glycolysis

24
Q

what is the net products of glycolysis

A

2 NADH
2 ATP
2 pyruvates

25
Q

what is glycogen converted into for glycolysis

A

G-6P

26
Q

what is pyruvate converted to and what is the product

A

acetyl-CoA

27
Q

what are the products of citric acid cycle

A

6 NADH
2 FADH2
2 GTP

28
Q

where do NADH and FADH2 enter after Krebbs cycle

A

ETC

29
Q

how much ATP is produced from 1 glucose

A

32

30
Q

what’s the bond removed from ATP phosphate groups called

A

phosphoanhydride bonds

31
Q

which phosphate group is removed

A

the gamma one

32
Q

does ATP have a ribose or deoxyribose sugar

A

ribose

33
Q

how is glucose converted to glucose 1-phosphate

A

hexose kinase
isomerase

34
Q

which enzyme converts to UDP-glucose from glucose 1-phosphate

A

uridyl transferase

35
Q

how is glycogen prepared to become glucose 6 phosphate

A

catabolism

36
Q

which bilayer does cholesterol stiffen

A

glycerophospholipid

37
Q

which bilayer does cholesterol make more fluid

A

sphingolipid

38
Q

what do lipid rafts do

A

allows for cell signalling

39
Q

do lipid droplets have one or 2 layers

A

1

40
Q

how does a lipid droplet formed

A
  • triacylglycerol is pumped into bilayer
  • buds off from SER
41
Q

how many times does the fatty acid synthase happen

A

7 times

42
Q

what is the name of the most common FA and how many carbons

A

palmitic acid and 16 carbons

43
Q

how is arachidonic acid made

A

synthesised through linoleic acid

44
Q
A