W28/L7 Flashcards

1
Q

In which type of bone do we find the haversian systems?

A

Compact

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2
Q

What’s another name for haversian systems?

A

Osteons

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3
Q

What’s the name of the space that osteocytes live in?

A

Lacunae

Can also refer to the space in cartilage where the chondrocytes live

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4
Q

What are the histological features of active osteoblasts?

A

Amphophilic cytoplasm

Paranuclear hoff

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5
Q

Where do the osteoid progenitor cells live?

A

In the ‘osteum (peri- and endo-)

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6
Q

What are the 4 phases of fracture healing?

A

Infammatory phase
Reparative phase: soft callus
Reparative phase: hard callus
Remodelling phase

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7
Q

In a fracture - how long does it take for granulation tissue to form?

A

A few days, though about a week to get “good” granulation tissue

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8
Q

What happens in the inflammatory phase of fracture repair?

A

Formation of a haematoma, and granulation tissue

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9
Q

What happens in the soft callus part of the reparative phase of fracture repair?

A

There’s cartilage formation that holds the fractured ends together

The periosteum repairs itself

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10
Q

What happens in the hard callus part of the reparative phase of fracture repair?

A

Woven bone formed by osteoid formation & ossification

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11
Q

What’s the time frame after fracture for soft callus formation?

A

Days-weeks

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12
Q

What’s the time frame after fracture for hard callus formation?

A

Weeks-months

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13
Q

What happens in the remodelling phase of bone fracture repair?

A

The woven bone becomes lamellar bone, and the bone is back to normal

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14
Q

What’s the time frame after fracture for the remodelling phase?

A

Months-years

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15
Q

In what case might fracture repair skip the soft callus phase?

A

When the ends are closely apposed

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16
Q

What’s the medical term for minimising the gap between two ends of broken bone?

A

Reduction of the fracture

17
Q

What factors can slow healing of a fracture?

A
Poor blood supply
Infection
Smoking
Old age
Co-morbidities
NSAIDs & corticosteroids
18
Q

What bug usually causes osteomyelitis in open fractures?

A

Staph aureus

19
Q

What’s another term for open fractures?

A

Compound

20
Q

What are two common sites of fracture causing osteonecrosis?

A

NoF

Scaphoid

21
Q

From which two cancers are bony mets most likely to arise, and what proportion is meant “most”?

A

Breast
Prostate

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