W2 What is pharmaceutics?

Question 1

What is the definition of pharmaceutics?

Answer 1

Pharmaceutics describes the conversion of a drug to a medicine

Question 2

Different names for “drug”

Answer 2

Active ingredient
Medicinal agent
Pharmacological agent
Active principal
Therapeutic
Active pharmaceutical ingredient (API)

Question 3

Different names for “medicines”

Answer 3

Dosage form
Formulation
Preparation
Medicinal product
Pharmaceutical product

Question 4

What are excipients?

Answer 4

Inactive ingredients

Question 5

What is the definition of biopharmaceutics?

Answer 5

Biopharmaceutics: study of how the physicochemical
properties of the drug & medicine combine with
physiological aspects of the delivery route to determine rate and extent of absorption

Question 6

What is definition of the formulation of medicines?

Answer 6

Act of designing and producing a medicine from first principles

Question 7

Process of formulation of medicines and the final medicine (or dosage form) depends on many factors including:

Answer 7

– Physicochemical properties of the drug
– Biopharmaceutics
– Disease factors
– Patient acceptability

Question 8

What is Preformulation?
What needs to be understood during this period?

Answer 8

-Everything that needs to happen first
with a new drug candidate
-Drug: solubility, melting point, pKa, log P etc.

Question 9

When is small scale manufacturing required?

Answer 9

when developing new formulations
when no commercial product is available: specials manufacture or compounding

Question 10

Why are microorganisms dangerous in pharmaceutics?

Answer 10

-Microorganisms can cause diseases and they also have the capacity to spoil medicines
-Contaminated medicines can be lethal
-The number of microorganisms acceptable in a medicine depends upon the type of dosage form, e.g. tablets vs injections