Von Willebrand Disease

Question 1

Von Willebrand disease

Answer 1

A genetic disorder that results in the reduced ability to create blood clots

• caused by mutation of deficiency in von Willebrand factor in clotting factor VIII

Question 2

Signs and symptoms of von Willebrand disease

Answer 2

Frequent, prolonged, or severe episode of bleeding

Easy bruising

Question 3

Management of von Willebrand disease

Answer 3

• Desmopressin DDAVP

Recombinant von Willebrand factor concentrate