Idiopathic thrombocytopenia Purpura

Question 1

Idiopathic thrombocytopenia Purpura

Answer 1

Thrombocytopenia resulting from autoimmune destruction of platelets with or without suppression of thrombopoiesis

Question 2

Platelets

Answer 2

150-400

Question 3

ITP

incidence

Answer 3

In adults ITP is usually chronic causing mild to sphere thrombocytopenia
Only occasionally do patients develop bleeding that require hospitalization
Women outnumber men in incidents by a ratio of three to one

Question 4

Lab and diagnostics for ITP

Answer 4

Bone marrow analysis
Low platelet count with other causes of thrombocytopenia ruled out; there may be a history of easy bruising or bleeding- gums and kidneys first

Question 5

Management of ITP

Answer 5

May not be necessary until platelets less than 20
High dose quartercoaster steroids may help elevate the platelet count within 2 to 3 days
IV Gamma globulin usually produces a response within 2 to 3 days
Platelet transfusion‘s may occasionally benefit

Question 6

Thrombocytopenic precautions

Answer 6

Avoid consumption (increase fiber, laxatives)
No flossing
No shaving
Cold pressure for five minutes or more for cuts, line insertion

Question 7

Heparin induced thrombocytopenia purpura management

Answer 7

Argatroban

Lepirudin

Question 8

How to differentiate ITP from SLE

Answer 8

Bone marrow analysis