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Hematologic And Oncologic Disorders > Pernicious anemia > Flashcards

Pernicious anemia Flashcards

1
Q

Pernicious anemia

A

Macrocytic
Normochromic
Due to deficiency of intrinsic factor, which results in malabsorption of B12

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2
Q

Signs and symptoms of pernicious anemia

A
  • neurological deficits
  • glossitis
    Weakness
    Palpitations
    Dizziness
    Anorexia
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3
Q

Lab and diagnostics for pernicious anemia

A

Low HGB, HCT, RBC
High MCV
Serum B12 < 200

Anti- IF and anti-parietal cell antibody test

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4
Q

Low B12

A

<200

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5
Q

Management of pernicious anemia

A

B12 100mcg daily x1 week, then monthly for life

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Hematologic And Oncologic Disorders (12 decks)

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