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First Aid Stuff I Don't Know > Vol. V - MSK, Rheum, Derm > Flashcards

Vol. V - MSK, Rheum, Derm Flashcards

1
Q

Trapezius is innervated by

A

accessory nerve

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2
Q

Cell mediating dermatomyositis

A

CD4 T cells –> perimysial inflammation

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3
Q

Tibial nerve roots

A

L4-S3

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4
Q

Most common causes of septic arthritis

A

S.aureus, Strep, N. gonorrheae

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5
Q

location of osteosarcoma

A

metaphysis of long bones

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6
Q

femoral nerve roots

A

L2-L4

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7
Q

Obdurator nerve innervates

A

sensory - medial thigh

motor - adductors, obdurator, pectineus

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8
Q

iliohypogastric nerve innervates

A

sensory - suprapubic region

motor - transversus abdominus and internal oblique

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9
Q

axillary nerve roots

A

C5-C6

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10
Q

Acetaminophen mechanism

A

reversible inhibits COX, mostly in CNS (not anti inflammatory)

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11
Q

Abnormal labs in osteomalacia/rickets

A

decreased Ca, decreased PO4, increased ALP, increased PTH, vitamin D deficient

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12
Q

Abnormal labs in osteitis fibrosa cystica (secondary hyper pth)

A

decreased Ca, increased PO4, increased ALP, increased PTH

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13
Q

IT band syndrome

A

Overuse injury of lateral knee (e.g. in runners). Pain is 2/2 friction of the IT band on the lateral femoral epicondyle.

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14
Q

serratus anterior is innervated by

A

long thoracic nerve

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15
Q

Common (fibular) peroneal nerve roots

A

L4-S2

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16
Q

genitofemoral nerve innervates

A

sensory - scrotum/labia and medial thigh

motor - cremaster

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17
Q

RA involves

A

PIP, MCP, wrist

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18
Q

Zileuton blocks

A

5-Lipoxygenase (no Leukotrienes)

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19
Q

Type I muscle fiber properties

A

Slow, Red, uses Ox Phos, associated with endurance training

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20
Q

Peroneal/fibular nerve injury

A

foot drop

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21
Q

Abnormal labs in osteitis fibrosa cystica (primary hyper pth)

A

increased Ca, decreased PO4, increased ALP, increased PTH

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22
Q

contents of carpal tunnel

A

FDS tendons, FDP tendons, FPL tendon, median nerve

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23
Q

Limb compartment syndrome

A

increased pressure within fascial compartment of a limb –> venous outflow obstruction and arterial collapse –> anoxia and necrosis.

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24
Q

lunate dislocation can cause

A

median nerve impingement –> carpal tunnel

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25
Osteoarthritis presentation
improves with rest, asymmetric involvement, bowlegged
26
Leflunomide mechanism
Reversibly inhibits dihydroorate dehydrogenase --> blocks pyrimidine synthesis --> suppreses T cell proliferation
27
Median nerve roots
C5-T1
28
Prevention of pseudogout
colchicine
29
Guyon canal syndrome is caused by
compression of the ulnar nerve at the risk (e.g. cyclists)
30
hip abductors
gluteus medius, gluteus minimus
31
Sciatic nerve roots
L4-S3
32
tumor associated with vinyl chloride and arsenic
hepatic angiosarcoma
33
Effect of PGF2alpha
increased uterine tone
34
Effect of PGE1
decreased vascular tone
35
Treatment for Paget's disease of the bone (aka Osteitis Deformans)
bisphosphonates
36
Superior gluteal nerve roots
L4-S1
37
Abnormal labs in Paget disease
increased ALP
38
RA presentation
morning stiffness lasting > 1 hr, improves with use, symmetric involvement, systemic manifestations
39
synthetic PGE2
Dinoprostone
40
internal rotation of the hip
gluteus medius, gluteus minumus, tensor fascia lata
41
NSAID mechanism
reversible COX inhibition blocking prostaglandins
42
Treatment for Raynaud's
Ca channel blockers
43
tibial nerve injury presentation
can't stand on tiptoes (inversion and plantarflexion is lost)
44
Treatment for myasthenia gravis
AChE Inhibitor (pyridostigmine)
45
Cell mediating polymyositis
CD8 T cells --> endomysial inflammation
46
synthetic PGI2
Epoprostenol
47
iliohypogastric nerve roots
T12-L1
48
claw hand on digit extension
ulnar nerve injury
49
osteoarthritis involves
DIP and 1st CMC
50
Genitofemoral nerve roots
L1-L2
51
Inferior gluteal nerve roots
L5-S2
52
albinism pathophysiology
normal melanocytes with reduced melanin production due to decreased tyrosinase activity or defective tyrosine transport
53
Effect of PGE2
increased uterine tone
54
Scalded skin syndrome is caused by
Staph exotoxin destroying attachments in the stratum granulosum
55
Lat fem Q nerve innervates
sensory - anterior and lateral thigh
56
Type II muscle fiber properties
Fast, white, Anaerobic glycolysis, associated with strength and sprinting
57
RA serology
Anti-CCP is most specific, also se RF (anti IgG FC IgM Abs)
58
offending organism in an abscess is usually
S. Aureus
59
Abnormal labs in osteoporosis
decreased bone mass
60
crystals in calcium pyrophosphate deposition disease
aka pseuodgout - crystals are rhomboid and weakly + bifringent
61
De Quervain tenosynovitis is caused by
Noninflammatory thickening of apl and epb tendons --> pain and tenderness at radial styloid
62
Presentation of radial head subluxation
(aka nursemaids elbow) injured arm is slightly flexed and pronated.
63
Diffuse scleroderma serology
anti-scl-70 (DNA topoisomerase) and anti-RNA-pol-III
64
Radial nerve roots
C5-T1
65
wrist drop
radial nerve injuriy
66
Classic gout presentation
painful MTP joint of big toe
67
Mixed connective tissue disorder serology
anti-U1 RNP
68
Deltoid is innervated by
axillary nerve
69
Musculocutaneous roots
C5-C7
70
hip flexors
iliopsoas, rectus femorus, tensor fascia lata, pectineus, sartorius
71
location of Ewing Sarcoma
diaphysis of long bones
72
Probenecid mechanism
inhibits reabsorption of uric acid in the PCT
73
Muscles int he rotator cuff
Supraspinatis, infraspinatus, teres minor, subscapularis
74
Lat fem Q nerve roots
L2-L3
75
Trandeleburg sign
superior gluteal nerve injury (med and min) contralateral to drop
76
Femoral nerve innervates
sensory - anterior thigh and medial leg | motor - quadriceps, iliacus, pectineus, sartorius
77
Abnormal labs in osteopetrosis
may see decreased serum Ca on severe cases, dense, brittle bones
78
SLE serology
ANA, anti-dsDNA, anti-Sm, antiphospholipid, SS-A, SS-B
79
external rotation of the hip
iliopsoas, gluteus maximus, piriformis, obdurator
80
superficial laceration of the hand can damage/cause
recurrent branch of the median nerve --> ape hand and loss of thenar muscles
81
hip extensors
gluteus maximus, semitendinosus, semimembranosus
82
Teripartide mechanism
PTH analog --> pulsatile dose increases osteoblast activity
83
Greenstick fracture
incomplete fracture from bending stress, bone fails on tension side, pediatric
84
synthetic PGF2alpha
Carboprost
85
vitiligo pathophysiology
destruction of melanocytes
86
most commonly fractures carpal bone
scaphoid (from FOOSH)
87
Sciactic nerver innervates
motor - hamstrings, adductor magnus
88
Obdurator nerve roots
L2-L4
89
Effect of LTC/D/E4
increased bronchial tone
90
Cause of achondroplasia
AD mutation causing constitutive activation of FGFR3
91
Aspirin mechanism
irreversibly inhibits COX by acetylation
92
hip adductors
adductor magnus, adductor longus, adductor brevis
93
synthetic PGE1
Alprostadil
94
Glucocorticoids block
phospholipase A2 and NF-kappaB
95
Abnormal labs in Hypervitamin D
increased Ca, increased PO4, decreased PTH
96
Effect of thromboxane A2
increased platelet aggregation and vascular tone
97
Drugs for chronic gout prevention
xanthine oxidase inhibitors: allopurinol, febuxostat
98
Torus (buckle) fracture
axial force --> cortex buckles on compression side, pediatric
99
Defect in Ewing Sarcoma
t(11;22) fusion protein
100
Sjogren syndrome serology
ANA, SS-A, SS-B, RF
101
inferior gluteal nerve innervates
gluteus maximus
102
anterior knee pain syndromes
Osgood-Schlatter disease (proximal tibial tubercle) and Patellofemoral (overuse made worse by sitting and weight bearing on a flexed knee)
103
Pudendal nerve roots
S2-S4
104
Nerve involved in carpal tunnel
median nerve
105
allele associated with seronegative spondyloarthritis
HLA-B27
106
benediction hand / ape hand
median nerve injury (can't flex or feel lateral three digits / thenar eminence)
107
Virus that mediates hairy leukoplakia
EBV
108
Bisphosphonate mechanism
bind hydroxyapatite in bone, inhibiting osteoclasts
109
Effect of LTB4
neutrophil chemotaxis
110
Effect of PGI2
aka prostacyclin, causes decreased platelet aggregation and vascular tone
111
Celecoxib mechanism
selective COX-2 inhibition

First Aid Stuff I Don't Know (10 decks)

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