Vitamins & Minerals Flashcards
Fat soluble, stored in the liver; carotene is precursor, provitamins converted in intestinal mucosa cells
Vitamin A
Functions of vitamin A
Skin and vision
Sources of vitamin A
Yellow, orange fruits; dark green leafy vegetables
Cantaloupe, fish, liver, carrots, fortified skim milk, apricots, sweet potato
Three results of vitamin a deficiency
Night blindness (nyctalopia) - reversible
Xerophthalmia (corneal damage) - not reversible
Dry, scaly skin (hyperkaratosis)
Precursor of vitamin D
Cholesterol
7 dehydrocholesterol –D3 cholecalciferol – D2 ergo calciferol
Rickets and osteomalacia are caused by deficiencies of what vitamin?
Vitamin D
Calcium and phosphorous metabolism is the function of…
Vitamin D
Egg yolk and fortified milk
Sources of vitamin D
Functions: antioxidant, resists destruction of RBC
Sources: vegetable oils, almonds, green vegetables, whole grains
Deficiency can lead to hemolytic anemia
Vitamins E / tocopherol
Synthesized by bacteria in lower GI Tract; forms prothrombin in the liver
Vitamin K
Needed for calcium metabolism. Deficiency can lead to hemorrhage.
Vitamin K
Vitamin K can be affected by:
Mineral oil, antibiotics, anticoagulants
Functions:
Oxidation of carbohydrates
Metabolism of pyruvate to acetyle CoA
Thiamin
Beriberi is a deficiency related to deficiency in:
Thiamin
Symptoms:
Muscle weakness, memory loss, tachycardia, loss of sensation
Beriberi
Sources of thiamin/B1
Grains, wheat germ, pork, liver
Thiamin deficiency can cause an increase in what lab value?
Plasma Pyruvate
Name for Vitamin B2
Riboflavin
Functions of riboflavin
Energy release from protein
Red cell production
Sources of riboflavin
Liver, kidney, meat, milk
Growth failure, cheilosis, angular stomatitis, and magneta tongue are symptoms of what deficiency?
Riboflavin
Nutrient essential in all cells for energy production and metabolism (carbs, protein and fat)
Niacin/B3
Sources of niacin
Protein, peanuts, cereal, chicken, rice, yeast, milk
Enrichment of grains include these vitamins:
Thiamin, riboflavin, niacin
What are the three D’s of pellagra?
Dementia, dermatitis, diarrhea
Pellagra and a beefy, bright red tongue are symptoms of what deficiency?
Niacin
Para-amino benzoin acid is precursor
Functions: DNA synthesis, forms RBC in bone marrow, prevents neural tube defects
Folate
Sources of folate
Fortified dry cereals, liver, kidney, green leafy vegetables, citrus fruits, lentils, beans
Folate deficiency leads to
Megaloblastic, macrocytic anemia
Diarrhea
Fatigue
Coenzyme in amino acid metabolism - deamination and transamination
B6/pyridoxine
Higher intake in protein requires increased
Pyridoxine/B6
Sources of B6
Meat and grains:
Meat, wheats corn, yeast, pork, liver, cereal
Deficiency symptoms:
Seizures, anemia, dermatitis, glossitis, peripheral neuropathy
B6
Cyanocobalamin
Contains cobalt
Bound by intrinsic factor in gastric juice
B12
Functions:
Coenzyme in protein synthesis
Forms red blood cells
B12
Sources of B12
Animal proteins:
Liver, meat, the milk, kidney, eggs, fish, cheese
Deficiency of B12 can lead to these two conditions:
Macrocytic, megaloblastic anemia
Pernicious anemia - after gastric tony or removal of ilium due to lack of intrinsic factor
Coenzyme A - energy
Synthesis of fatty acids
Pantothenic acid
Sources of Pantothenic acid
Animal foods, grains, legumes
Antioxidant
Changes proline into hydroxyproline into collagen which strengthens intercellular substances
Wound healing
Aids iron absorption
Vitamin C
Sources of vitamin C
Citrus fruits, potatoes, papaya, dark green, yellow vegetables
Scurvy is characterized by poor wound healing, bleeding gums, and petechia. This is a symptom of what vitamin deficiency?
Vitamin C
Synthesized by intestinal bacteria, inactivated by avidin
Biotin
Coenzyme in fatty acid synthesis
Converts pyruvate to oxaloacetate in gluconeogenesis
Biotin
Sources of biotin
Liver, kidney, egg yolk, yeast
Deficiency symptoms:
Muscle pain
Dermatitis
Glossitis (inflammation of tongue)
Biotin
Four functions of calcium
Blood clotting
Cardiac function
Nerve transmission (release of neurotransmitters)
Smooth muscle contractility
Most abundant mineral
Regulated by parathyroid hormone
Vitamin D, acid, lactose aid absorption
Calcium
Sources of calcium
Dairy, leafy vegetables, legumes
Deficiency leads to tetany(stiff muscles)
Calcium
Functions of phosphorous
Part of DNA and RNA
Phospholipids transport fat through lymph and blood
Bones
Teeth
Sources of phosphorous
Animal proteins
Meat, fish, poultry, eggs, fish, cheese
Iron function
Oxygen transport
Iron deficiency
Pale tongue, fatigue
Anemia
Spoon-shaped nails
Pale conjunctivae (mucous membranes lining eyelid)
In most foods, milk,bread
Magnesium
Protein and fatty acid synthesis
Stabilizes structure of ATP
High pro, calcium, vit D increase need
Magnesium
Magnesium deficiency is rare, but could cause….
Tremors
Excess less to copper or iron absorption
Zinc
Functions of zinc
Increases taste acuity
Enhances insulin action
Stabilizes DNA, RNA
Cell division
Sources of zinc
Animal proteins
Meat, liver, eggs, fish
Reduced immune function
Alopecia
Poor wound healing
Hypogeuisia
Zinc deficiency
Sources of iron
Heme: animal foods, meat, fish, poultry
Non-heme: cereal, vegetables
Absorption of iron is enhanced by
Vitamin C
Calcium if oxalates are present
The following do not aid in absorption of iron
Eggs
Tea
Milk
Cheese
50% in bone
50% in cells
Part of chlorophyll
Magnesium
Iodine sources
Seafoods, iodized salt
Iodine deficiency
Goiter
Part of thyroxine
Iodine
Functions of fluoride
Teeth and bone
Sources of fluoride
Soil
Water
Fluoride deficiency
Dental caries
Copper functions
Hemoglobin synthesis
Aids iron absorption
Sources of copper
Liver, kidney, shellfish
Deficiency symptoms:
Microcytic anemia
Neutropenia
Wilson’s disease (low serum copper, genetic absence of liver enzyme)
Copper
Cooperates with vitamin E
Antioxidant
Tissue respiration
Selenium
Sources of selenium
Soil, grains
Animal protein: meat, fish, poultry, dairy
Deficiency symptoms:
Myalgia
Cardiac myopathy
Selenium
Function: central nervous system
Manganese
Sources of manganese
Whole grains, legumes, nuts
Absorption enhanced with vitamin C and niacin
Aids insulin action
Glucose metabolism
Chromium
Sources of chromium
Yeast, oysters, potatoes, liver
Chromium deficiency
Insulin resistance
Exists with B12
Maturation of red blood cells
Deficiency related to B12
Cobalt
Part of amino acids cysteine, cystine, methionine
Component of organic molecules
Sulfur
Sources of sulfur
Animal proteins:
Meat, fish, eggs, poultry
Choline is a component of ….
Lecithin
Function of choline
Transports lipids as acetylcholine
Sources of choline
Fat in eggs, lived, milk, soybeans