Vitamins Flashcards
Water soluble vs Fat soluble Absorption, transport, storage, excretion, toxicity, requirements
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Factos effecting bioavailability
- efficiency of digestion/transit time
- previous nutrient intake
- other foods consumed simultaneously
- food preparation method
- source of the nutrient - synthetic or natural
Thiamine - function
coenzyme of carb metabolism (energy yielding)
wet vs dry beriberi
wet - odema, CVD failure
Dry - pain, tingling, loss of sensation
Wernicke - encephalopty
alcohol related rain damage - language problems, walking difficulty
Korsakoff syndrome
amnesia, inavility to learn, confabulation
Thaimine foods
wholegrain cereals, fortified foods, legumes, sunflower seeds, pork
Folate funciton
coenzyme for DNA syntehsis
Folate deficiency
Macrosytic anaemia, poor growth, NTD e.g spina bifida
Folate foods
GLF, legumes, seeds, liver, fortified cereals
Cause of folate deficiency
low intake reduced absorption drugs high alcohol intake pregnancy (Increased requirement)
Folate requirement pregnacy
800ug/day 4 weeks prior or 5000ug/day previous history
Vitamin A - function
Vision night and colour, health of cornea, prevent drying of skin and eyes (maintains healthy mucous membranes)
Keratinisation
bumpy skin, poor immune response
Xerothalmia
night blindness - vit A deficincy
Vit A toxicity - beta carotine and retinol
beta - overconsumption of food, ineffecient conversion - can go orange
Retinol - overconsumption from supplements e.g acne mediciation
Vit A foods
retinol - eggs, dairy
Beta carotene - GLF, deep orange F and V
Function of Vit D
increase absorption of calcium, phosporous, miantains optimum blood calcium and calcification of bone, regulates immune function and cell growht
Vit D deficiency
Rickets in children, osetomalacia in adults
Vit D - conversion to active form
7 dehydrocholesterol in skin, sun to vit D3, then in liver to 25-hydroxy vit D, kidney - 1-25 dihydroxy vit D - active form
Food sources of Vit D
liver, fatty fish, salmon, milk, egg
People who need supplements
Poor nutrient intake (elderly, dieters, vegeterians)
Increased nutreitn requirements (preg, children, lactation)
Increased metabolic demands (surgery, trauma)
Maldigestion and malabsorption
Drug nutrent interactins
Medical treatment interacitons