vitamins Flashcards
water soluble Vitamins?
fat soluble Vitamins?
Vitamins A,E,D,K fat soluble
Vitamins B,C water soluble
How vitamins absorption?
water soluble absorbed into blood stream kidney fitter out excesses and excrete in urine
fat soluble micelles carry to the brush border in small intestine absorption chylomicrons contain Vitamin transported via a blood stream to liver
hydrophilic and hydrophobic
hydrophilic親水的分子能透过 氢键氢键 和水形成键结吸引水分子或易溶于水.
hydrophobic疏水性(或斥水性、拒水性)指的是一個分子與水互相排斥的物理性質
Vitamins absorb from?different between fat and water soluble?
all in small intestine
water soluble
黏膜肥大細胞(mucosal mast cell) to blood vessel to urine
fat soluble
micelles is bile acid+lipid+fat soluble vitamin throw microvilli change to chylomicron to lymph vessel to liver
Vitamin A precursor?
come from?
Ex: food?
egg/milk/liver/cod雪魚/fish oil - well absorbed than plants
carotenoid carrots,cantaloupe,sweet potato,spinach
green leafy vegetable
red, orange fruit or vegetable
beta carotene ( carotenoids) change to Vit A
types of vitamin A? x 3
function?
retinol
for reproduction and bone health
immunity
retinal
for nigh and colour vision
retinoic acid
cell growth
cell differentiation with DNA to different stem cells into different cell type
retinol ><retinal> retinoic acid</retinal>
Vit A deficiency?
overdose?
night blindness/ eye disorders
too much beta carotene turn skin to yellow or orange
diarrhea, headache, nausea, can damage liver and bones
why too much Vitamin A lead to osteoporosis?
retinoic acid (which the body makes from vitamin A) stimulates osteoclasts 蝕骨細胞but suppresses osteoblast成骨細胞
RDA vit A? mcg
damage ?
900 mcg/day
Vitamin A in high doses is a direct toxin
vitamin A is stored in stellate cells in the liver excess collagen production, fibrosis and liver injury.
Body can synthsize Vit ? with sunshine
How?
Vit D
sun > 7-dehydrocholesterol>cholecalciferol Vit D3
>liver> 25-hydroxyvitamin D3 > kidney maintains calcium/ phosphate balance> bone
Vit D food?
fish, salmon , tuna, fish oil
small amount in cheese, egg yolks
Deficiency of Vit D?
overdose?
osteoporosis
Rickets
=calcium loss lead to bone soften in children
osteomalacia = o sharp leg
ovrdose: high calcium
vomiting, poor appetite, constipation, weakness and weight loss
which vitamin is anti aging?
chemical name?
function? x 3
RDA?
RDA 10 mg/day
vit E tocopherol
an antioxidant against free radical attack
protect lungs against oxidative damage from environment
prevent cancer against DNA mutating變異
dietary in Vit E?
too much counters to ?
corn, nuts, oliver, green leafy vegetable, vegetable oil and wheat germ
large dose Vit E or A counters Vit K
blood clotting mechanism
Vit k name?
function?
How?
Koagulation
promote blood clotting
assists bone formation
allow the protein to strengthen skeleton
pletelets > prothrombin> thrombin> fribrinogen>fribrin>frbrin clot