Vitamins Flashcards

1
Q

Vitamin D can be formed by _____ and naicine from_____ by the body

A

Cholesterol
Tryptophan

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2
Q

Vitamins can be classified into

A

Water soluble and fat soluble

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3
Q

Water soluble fats includ

A

Vitamin
B1( thiamine)
B2 ( Ribuffaxin)
Naicine ( nicotinic acid)
B5 (Pantothenic acid)
B6 (pyrodoxine)
Biotin
Vit. B12 (Cobalamin)
Folic acid
And C (accorbic Acid)

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4
Q

When phosphorus is added to thaimine it’s converted?
It’s function

A

Thaimine Pyro phosphate which is a coenzyme for decarboxylation of keto acids

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5
Q

What are the enzymes that use TPP

A

Pyruvate decarboxylase
Pyruvate dehydrogenase
Branched chain alpha keto acid dehydrogenase
Alpha keto glutamate dehydrogenase
Transketolase

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6
Q

What are the sources of thaimine
Minimum requirements

A

Seeds, nuts, wheat, legumenious plants, lean meat
Adult–1. 0mg,
Infant& children–0. 4-1.3mg

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7
Q

Required intake increase in cases such as

A

Anoxia- shock, hemorrhage, hyperthyroidism, injury, illness, fever, pregnancy, lactation, increased carbohydrates intake

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8
Q

Deficiency in thiamine causes

A

Dry Beri beri & wet beri beri
Due to low plasma albumin and congestive cardiac failure

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9
Q

Symptoms of thiamine deficiency

A

Exhaustion, neuropathy, anorexia, cardiac disorders
Wenicke korsakoff syndrome found in alcoholic associated with thiamine deficiency

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10
Q

_____ is the component of the coenzyme FAD and FMN

A

Riboflavin, vit.B2

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11
Q

Riboflavin has ____ ring system binked by_____, which allows riboflavin to exist as____ and accept electrons either as pair or single

A

Isoalloxazine
Linked by ribitol
Exist as semiquinone

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12
Q

____ and ____ can only accept electrons as pairs?

A

NAD & NADP

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13
Q

FMN and FAD is ____ dependent

A

Atp dependent

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14
Q

Riboflavin is mainly used in?

A

Energy metabolism of lipid and sugar

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15
Q

Sources of riboflavin

A

Meat, nut, legumes, milk, fish, egg

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16
Q

Normal riboflavin in adults, infants and children

A

Adults–1. 5-2.5
Infants–0. 6
Children–1-1. 8

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17
Q

Lack of riboflavin is non-fatal

A
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18
Q

Y Is nicotinic acid not really considered a vitamin

A

Bcuz it can be formed by tryptophan but it’s inefficient
60mg for 1

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19
Q

Nicotinic acid contains a ___ ring

A

Pyridine

20
Q

Sources of nicotinic acid

A

Milk, lean meat, unrefined grain, cereals, tryptophan

21
Q

Required nicotinic acid

A

For adults– 17-21
Infant–6mg

22
Q

Deficiency in nicotinic acid causes

A

Pellagra
Diseases involving GIT & CNS

23
Q

Deficiency of Pyrodoxal phosphate causes

A

Hypo chronic microcytic anemia
In infant causes convulsiin due to inactive glutamate decarboxylase

24
Q

Bitulin is a coenzyme associated with

A

Carboxylation rxn

25
Q

Sources of bitulin

A

Intestinal bacteria, liver, egg, peanut, milk

26
Q

What can cause deficiency in bitulin

A

Excess consumption of white part of egg

27
Q

Cabalanin(B__) has ____ ring

A

B12 tetrapyridine ring

28
Q

B12 deficiency causes

A

Lack of intrinsic factors
Pernicious anemia

29
Q

Active form of folic acid is

A

Tetra hydro folate THF

30
Q

Folic acid deficiency results in

A

Megaloblastic anemia, impaired absorption, neural tube defects

31
Q

Burning foot syndrome is due to deficiency in?

A

Pantothenic acid B5

32
Q

What vitamin forms an essential part of acetyl carrier moiety

A

Pantothenic acid B5

33
Q

vit.C is also known as

A

Ascorbic acid

34
Q

The H-bond in vit.C are

A

Triple hellix

35
Q

Deficiency in vit. C causes

A

Scurvy– weakening of collagin fibres
Failure to hydroxylate proline and lycine

36
Q

Hydroxylation reactions requires

A

Vit. C

37
Q

What vit. are fat soluble
Which serves as coenzyme

A

A, D, E, K
Only K
Vit. D is more like a hormone

38
Q

Vit. A are present in diet as

A

Retinol & beta carotene

39
Q

Deficiency in vit. A causes

A

Night blindness

40
Q

Vit. D deficiency results in

A

Obstructive jaundice, partial gastronomy, GOT disorders, Ricket

41
Q

Deficiency of vit. E only in pregnancy & new born baby

A

Hemolytic anemia

42
Q

Vitamin E occurs in diet as 8 closely related compounds called

A

Tocopherol

43
Q

Vitamin K are of ___ types?
Absorption of vitamin K&E is dependent on

A

3 types
Menaquinone(K2) in animals
Phylloquinone(K2) in plants
Appropriate fat absorption

44
Q

_____ acts as q coenzyme for fat soluble vitamin

A

Vitamin K

45
Q

Hh

A