Protein META

Question 1

The amount of nitogen excreted in a day is = amount consumed daily as dietary proteins
TRUE OR FALSE?

Answer 1

True

Question 2

During tissue growth, growing children, or after surgery
Nitrogen balance is =

Answer 2

Intake is greater than output
Since there’s nitrogen retention for building new tissues

Question 3

In fever, starvation or cachexia nitrogen balance is -very
True or false

Answer 3

True
Intake is less than loss

Question 4

During lactation and pregnancy the nitrogen balance is?

Answer 4

Positive

Question 5

The amount of protein synthesized and broken down in a day is?

Answer 5

300-400g/day
350-400g/day

Question 6

The amount of amino acids poll in the body is?

Answer 6

100gm

Question 7

All amino acids are transaminated except?

Answer 7

Lysine, threonine, proline
They follow a degredative pathway

Question 8

Transanimation takes place in ____ part of the cell

Answer 8

Cytoplasm

Question 9

Oxidative deamination takes place in ____ part of the cell?

Answer 9

Mitochondria

Question 10

Metabolism of amino acids can lead to the production of?

Answer 10

ATP, Non essential amino acids, glucose( gluconeogenesis), formation of lipids

Question 11

What amino acid reacts with alpha krto glutamate to form Oxaloacet and glutamate?

Answer 11

Asparate and asparagine

Question 12

What amino acid reacts with alpha krto glutamate to form fumarate and glutamate?

Answer 12

Phenylalanine and tryosine

Question 13

What amino acid reacts with alpha krto glutamate to form pyruvate and glutamate?

Answer 13

Alanine, Glysine, Serine,Cysteine, Tryptophan and Threorine

Question 14

What amino acid reacts with alpha krto glutamate to form alpha keto glutamate and glutamate?

Answer 14

Glutamate—–Arginine, Glutamine,Histidine, Proline

Question 15

What amino acid reacts with alpha krto glutamate to form Acetyl CoAand glutamate?

Answer 15

Leucine, Tryptophan, Threonine, Isoleucine

Question 16

The coenzyme of Transamination is?

Answer 16

Pyridoxal Phosphate ( Amino Tranferase)

Question 17

What’s deamination?

Answer 17

The removal of nitrogen from amino acids as NH4

Question 18

Oxidative deamination is catalyzed by?

Answer 18

Glutamate dehydrogenase or Amino acid oxidase

Question 19

Non Oxidative deamination is catalyzed by?

Answer 19

Amino acid dehydratase
And AA disulphydeatase

Question 20

What’s the function of oxidative deamination by glutamate dehydrogenase Catabolically and Anabolically?

Answer 20

Cata— channels N from glutamate to ammonia
Ana– catalyzes amination of alpha keto glutamate to glutamate

Question 21

What amino acid undergo non- oxidative deamination?

Answer 21

AA dehydrogenase
Serine, homoserine and threonine
AA disulfhydrase
Cysteine and homo cysteine

Question 22

Histidine undergoes what type of deamination?
And is deaminated to ______

Answer 22

Non oxidative
Urocanate

Question 23

The ammonia produced in the brain and the muscles are trapped by ____ and _____ to form _____ and ______ before sending it to the liver?

Answer 23

Glutamic acid and asparic acid
Glutamine and asparagine
The glutamine is reversed back to glutamic acid in the liver by glutaminase

Question 24

Urea cycle is connected to the kreb cycle by_____ at ____ step?

Answer 24

Fumarate
@ step4

Question 25

______ ATP is consumed to form 1 molecule of urea?
And how many is produced?

Answer 25

4 ATP
2.5 ATP @ malate—oxaloacetate
NET = -1. 5 ATP

Question 26

What are the significance of urea cycle?

Answer 26

Detoxification of NH3
Disposal of waste products nh3 and biocarbonate
Regulation of pH
Bio synthesis of argenine

Question 27

What’s the difference between CPS1 AND CPS2?

Answer 27

Cps1– mitochondria, requires cofactor NAG, urea synthesis, no inhibitor, Ammonia-N- donor

Cps2– cytosol, doesn’t require cofactor, pyrimidine synthesis, CTP inhibitor, Glutamate-N-donor