Viruses

Question 1

DNA Viruses

Answer 1

HHAPPPPy
Hepadna
Herpes
Adeno
Pox
Parvo
Papilloma
Polyoma

Question 2

Herpes Viruses

Answer 2

DNA virus
HSV-1 → Saliva
HSV-2 → sexual
HHV-3 → Varicella-Zoster (Herpes zoster)
HHV-4 → EBV
HHV-5 → Cytomegalovirus
HHV-6,7 → Roseola
HHV-8 → Kaposi sarcoma

Question 3

EBV

Answer 3

Epstein-Barr virus (HHV-4)
Mononucleosis from teens kissing
hepatosplenomegaly, lymphadenopathy (posterior cervical), pharyngitis
Lymphomas → Burkitt, nasopharyngeal carcinoma (asians)
amoxicillin → maculopapular rash

Question 4

CMV

Answer 4

cytomegalovirus (HHV-5)
infections in immunocompromised →
Retinitis, esophagitis (linear ulcerations)
Owl eye intranuclear inclusions

Healthy adult infections → asymptomatic or mono-like

Congenital CMV (ToRCHeS)
blueberry muffin
hearing loss
siezures
chorioretinitis
periventricular (Brain) calcifications

Question 5

Roseola

Answer 5

HHV-6, HHV-7
fevers
seizures
rash that spares face
fever first → rash later

Question 6

Hepadnavirus

Answer 6

Hepatitis B

DNA virus

Question 7

Adenovirus

Answer 7

DNA virus
infects adenoid tonsils
acute hemorrhagic cystitis
common cause of pink eye

Question 8

Papillomavirus

Answer 8

DNA virus

HPV-16, 18 → cervical cancer

Question 9

Polyomavirus

Answer 9

DNA virus
JC → junky cerebellum (progressive multifocal leukenphalopathy)
BK → bad kidney (after transplant, nephropathy, hemorrhagic cystitis)

Question 10

Parvovirus

Answer 10

DNA virus (single stranded)
“slapped cheek” rash in children
aka fifth disease or erythema infectiosum

Hydrops fetalis
aplastic crisis in sickle cell patients

Maternal symptoms: arthritis

Question 11

Picornaviruses

Answer 11

Rhinovirus
Hep A
Coxsackievirus
Polio
Echovirus

Question 12

Coxsackievirus

Answer 12

Picornavirus (RNA)
A: Hand, Foot, and Mouth disease
Aseptic meningitis

B: pericarditis, myocarditis, bornholm disease (stabbing chest pain)

Question 13

Norovirus

Answer 13

Calciviruses

cruise ship diarrhea (Watery)

Question 14

Flaviviruses

Answer 14

Hep C
Yellow fever → high fever, jaundice, hemorragic vomit, diarrhea
Dengue
St. Louis encephalitis
West Nile virus
Zika virus → Aedes mosquito, causes miscarriage

Question 15

Togavirus

Answer 15

Toga CREW
Chikungunya virus
Rubella
Eastern and Western equine encephalitis

Question 16

Rubella

Answer 16

Togavirus (RNA)
Fever
post-auricular and occipital lymphadenopathy
fine maculopapular rash starts on face and descends

ToRCHeS infection → blueberry muffin rash

Question 17

Orthomyxovirus

Answer 17

Influenza virus

Question 18

Filoviruses

Answer 18

Ebola, Marburg hemorrhagic fever

Question 19

Paramyxoviruses

Answer 19

PaRaM
Parainfluenza → croup
RSV
Mumps
Measels (Rubeola)

Question 20

Mumps

Answer 20

Paramyxovirus
Parotitis (parotid tonsil)
Orchitis → sterility possible
Meningitis
pancreatitis

Question 21

Rubeola

Answer 21

aka Measels
Paramyxovirus
Koplik spots (bright red with white-blue centers)
Maculopapular rash which descends
pneumonia
Vit A supplementation recommended

Sequelae years later:
subacute sclerosing panencephalitis
encephalitis
giant cell pneumonia

Question 22

Hepatitis D

Answer 22

HBV superinfection

D = Depends on HBV infection

Question 23

Hepatitis E

Answer 23

Fulminant hepatits in prEgnant womEn
high mortality
fecal oral

Question 24

ToRCHeS infections

Answer 24

microbes which can pass from mother to fetus
Toxoplasma ghandii → brain, eye
Rubella → eye, ear, heart
CMV → brain, eye, ear
HIV → HIV
HSV type 2 → brain
Syphilis → stillbirth, saddle nose, saber shins, deaf

Question 25

Blueberry muffin baby

Answer 25

Toxoplasma ghandii
Rubella
CMV