Viruses

Question 1

Influenza virus

Answer 1

Enveloped ssRNA
Fever, muscle aches and chills, respiratory distress
Hemagglutinin, neuraminidase
PCR, serology, immunofluorescence

Question 2

Human immunodeficiency virus (HIV)

Answer 2

Enveloped (+)ssRNA
mononucleosis like illness
Targets are CD4 cells
PCR, ELISA

Question 3

Enteroviruses

Answer 3

Naked (+)ssRNA
Paralytice disease, acute inflammation
Long survival, cause cell lysis, destroing of motor neuron cells (polio)
PCR

Question 4

Herpes simplex virus

Answer 4

Enveloped dsDNA
fever, blisters and ulcers
Become latent, giant cells
PCR, immunofluorescence

Question 5

Varicella zoster virus

Answer 5

Enveloped dsDNA
Chickenpox, fever, rash and shingles
Latent in sensory ganglion cells
Clinical, immunofluorescence

Question 6

Cytomegalovirus

Answer 6

Enveloped dsDNA
Mononucleosis syndrome, congenital infection, pneumonia, retinitis in patients with impaired cellular immunity
Latent in leukocytes, direct tissue damage
PCR, antigen detection, microscopy CMV (owl eye)

Question 7

Epstein-Barr virus

Answer 7

Enveloped dsDNA
Infectious mononucleosis: fever, mailaise, lymphadenitis
Infection of B cells
Serology

Question 8

Hepatitis-B virus

Answer 8

Enveloped dsDNA
Asymptomatic, limitid illness with fever and icterus
DNA polymerase, integration of viral genome in hepatocytes
Serology

Question 9

Respiratory syncytial virus (RSV)

Answer 9

Enveloped ssRNA
Bronchiolitis, common in infants
Adhesion, necrosis and inflammation of bronchioles
PCR, immunofluorescence