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MD1 > Immunoglobulins > Flashcards

Immunoglobulins Flashcards

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1
Q

IgG

A 
Maing ig
Monomere
Whole plasma
21-23 days half life
Can pass placenta
Opsonization and neutrolization
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2
Q

IgM

A 
Pentamere
Half life 5 days
CIrculation
First ig to be produced in fetus
Activation of classical pathway and complement
Poor toxin and viral neutralization
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3
Q

IgD

A

Membrane bound
Co-expressed on B-cells with IgM
Low serum concentration
Function unknown

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4
Q

IgE

A

Monomere
Half life unbound 2 days, bound 2 weeks
High affinity for mast cells

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5
Q

IgA

A 
Monomere or dimere
Half life 5.5 days
Mucosal system (gut, RT, UT)
Prevents colonization
Does not fix complement
Agglutination and antiviral activity
To baby by mothermilk
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MD1 (13 decks)

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