Viruses Flashcards
1
Q
What conditions are associated with Coxsackie A?
A
Hand, foot, and mouth disease Aseptic meningitis Herpangina Acute hemorrhagic conjunctivitis Poliomyelitis-like symptoms
2
Q
What conditions are associated with Coxsackie B?
A
Myocarditis
Pericarditis
Pleurodynia
Juvenile diabetes
3
Q
What is the pathogenesis of orthomyxoviridae?
A
Hemagglutinin on viral cell binds to sialic acid on host cell. When virus is being exocytosed, NA cleaves it.
4
Q
What is antigenic drift?
A
Small, constant point mutations Gradual change in amino acid composition Results in minor antigenic change leading to EPIDEMICS Seen in all 3 types of influenza Annual vaccine
5
Q
What is antigenic shift?
A
Substitution of gene segments with segments from another influenza virus from a different host –> reassortment
Only seen in influenza A
PANDEMICS
Less common
6
Q
What are the three strains of influenza?
A
A: humans, birds, swine, etc
B: only found in humans
C: mainly humans? (rare)
