Immunology Flashcards
1
Q
What is primary lymphoid tissue?
A
Where stem cells differentiate into either T cells (thymus) or B cells (bone marrow).
2
Q
What is secondary lymphoid tissue?
A
Where mature T/B cells go to encounter antigens.
3
Q
Where is secondary lymphoid tissue in the body?
A
Lymph nodes
Spleen
MALT (mucosal-associated lymphoid tissue) and other locations in the body with excess lymphatic accumulations
4
Q
What three activities take place in the thymus?
A
- Differentiation of thymocytes into T cells: early thymocytes express antigen receptors
- Self/non-self discrimination
- Elimination of self-reacting thymocytes
5
Q
What is involved in differentiation of thymocytes?
A
- Cell-to-cell contact with cortical epithelial cells and dendritic cells
- Thymic hormones
- Cytokines
