Viruses

Question 1

Can viruses reproduce by themselves?

Answer 1

No

They are obligate intracellular parasites

Question 2

How may viruses be biochemically classified?

Answer 2

RNA vs DNA

Then enveloped vs naked

Question 3

Name some enveloped DNA viruses:

Answer 3

Hep. B
Herpesviruses
Smallpox

Question 4

Name some naked DNA viruses:

Answer 4

Papillomavirus

Question 5

Name some enveloped RNA viruses:

Answer 5

Rubella
Rotavirus
HIV
Coronavirus
Ortho/paramyoxoviruses

Question 6

Name some naked RNA viruses:

Answer 6

Picornaviruses

Question 7

What is the baltimore classification?

Answer 7

A method of classifying viruses based on their genome and therefore their method of reproduction

Question 8

What is the host range of a virus?

Answer 8

For a virus to infect a cell, the cell must have a complementary receptor
The range of cells a virus may infect is its host range

Question 9

What is a viral capsid?

Answer 9

A protein outer coat that protects the genome

Question 10

What are the two basic capsid structures?

Answer 10

Helical and isochedral

Question 11

How may a virus cause cancer?

Answer 11

Turning on (or bringing) oncogenes
Inactivating TSGs 

e.g HPV (especially HPV-16 and HPV-18) produces E6/E7 proteins, which suppress the action of p53 and pRB.