Connective Tissue

Question 1

What are the two components of connective tissue?

Answer 1

Cells and ECM

Question 2

What are the components of ECM?

Answer 2

Ground substance and fibres

Question 3

What are the three types of connective tissue?

Answer 3

Loose, dense regular and dense irregular

Question 4

What is an example of loose connective tissue?

Answer 4

Colon submucosae

Question 5

What is an example of dense irregular connective tissue?

Answer 5

Dermis

Question 6

What is an example of dense regular connective tissue?

Answer 6

Tendon

Question 7

What is the role of fibroblasts?

Answer 7

Synthesis and secrete ground substance and fibres

Question 8

What is the role of macrophages?

Answer 8

Professional APCs, also phagocytosis nom nom nom

Question 9

What is the role of mast cells?

Answer 9

Contain granules e.g heparin or histamine
Release chemotaxins
Bind to IgE so mediate allergic reactions

Question 10

What cell types may be seen?

Answer 10

Fibroblasts
Macrophages
Mast cells
Adipocytes
(Plasma cells and leukocytes especially in inflamm)

Question 11

What fibre types may be seen?

Answer 11

Collagen (most abundant)
Reticular (type III collagen)
Elastic fibres

Question 12

What is ground substance?

Answer 12

Hyaluronate protein aggregate
Hyaluronic acid, with protein and GAGs branching off
Dense -ve charge to attract water