Viruses Flashcards

1
Q

What is a defining characteristic of viruses regarding size?

A

Viruses are small and have a fixed size, typically ranging from about 20 to 300 nanometers in diameter.

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2
Q

What type of genetic material do viruses contain?

A

Viruses contain nucleic acid as their genetic material, which can be either DNA or RNA.

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3
Q

What is a capsid in the context of viruses?

A

A capsid is a protein coat that encases and protects the viral nucleic acid, providing structural integrity to the virus.

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4
Q

Do viruses have cytoplasm?

A

No, viruses do not have cytoplasm; they are acellular and lack the cellular structures found in living organisms.

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5
Q

How do viruses differ from living cells in terms of enzymes?

A

Viruses possess few or no enzymes, relying on the host cell’s machinery for replication and metabolic processes.

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6
Q

Why is the structure of the capsid important for viruses?

A

The capsid protects the viral genetic material and aids in the attachment and entry into host cells, facilitating infection.

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7
Q

How does the absence of cytoplasm affect viral function?

A

The absence of cytoplasm means that viruses cannot carry out metabolic processes independently and must hijack host cellular machinery to replicate.

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8
Q

What implications does the lack of enzymes in viruses have for their classification as living organisms?

A

The lack of enzymes and cellular structures leads to the classification of viruses as non-living entities since they cannot reproduce or carry out metabolic processes on their own.

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9
Q

How does the size of viruses compare to that of bacteria?

A

Viruses are significantly smaller than bacteria, which typically range from about 0.5 to 5 micrometers in size, making viruses among the smallest infectious agents.

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10
Q

Why is it important to understand the structural features of viruses?

A

Understanding viral structure is crucial for developing vaccines, antiviral drugs, and diagnostic tools to combat viral infections effectively.

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11
Q

What is a key characteristic of viruses regarding their structural diversity?

A

Viruses exhibit a high degree of structural diversity in their shape and composition, which varies widely among different types.

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12
Q

What types of genetic material can viruses have?

A

Viruses can possess either DNA or RNA as their genetic material, which can be single-stranded or double-stranded.

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13
Q

How do enveloped viruses differ from non-enveloped viruses?

A

Enveloped viruses are surrounded by a lipid membrane derived from the host cell, while non-enveloped viruses lack this outer membrane and have only a protein capsid.

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14
Q

What is an example of a bacteriophage and its significance?

A

Bacteriophage lambda is an example of a virus that infects bacteria, illustrating the diversity of viral structures and their specific host interactions.

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15
Q

What structural features are common to coronaviruses?

A

Coronaviruses are enveloped viruses with spike proteins on their surface, which facilitate entry into host cells; they contain single-stranded RNA as their genetic material.

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16
Q

How does HIV exemplify viral diversity?

A

HIV (Human Immunodeficiency Virus) is an enveloped virus with a complex structure, containing two strands of RNA and various proteins that aid in its replication and infection process.

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17
Q

Why is the ability to have different types of nucleic acid important for viruses?

A

The variation in nucleic acid type (DNA or RNA) allows viruses to adapt to different hosts and environments, influencing their replication strategies and pathogenicity.

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18
Q

What role does the capsid play in viral structure?

A

The capsid protects the viral genetic material and aids in the attachment and entry into host cells, playing a crucial role in the virus’s ability to infect.

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19
Q

How does the presence or absence of an envelope affect viral stability?

A

Enveloped viruses are generally more sensitive to environmental conditions (like heat and detergents) than non-enveloped viruses, which tend to be more stable and resistant.

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20
Q

Why is it important to study the diversity of virus structures?

A

Understanding the diversity of viral structures helps inform vaccine development, antiviral therapies, and strategies for controlling viral infections in various hosts.

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21
Q

What is the lytic cycle in viruses?

A

The lytic cycle is a viral replication process where a virus infects a host cell, replicates its components, assembles new virions, and ultimately causes the host cell to lyse (burst), releasing new viruses.

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22
Q

How does a virus like bacteriophage lambda initiate the lytic cycle?

A

Bacteriophage lambda attaches to the surface of a bacterial host cell and injects its genetic material (DNA) into the cell.

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23
Q

What happens during the early phase of the lytic cycle?

A

After injection, the viral DNA takes over the host’s cellular machinery, redirecting it to synthesize viral components instead of normal cellular functions.

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24
Q

What occurs during the replication phase of the lytic cycle?

A

The host cell’s machinery replicates the viral DNA and produces viral proteins, leading to the assembly of new virions.

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25
Q

How are new virions assembled in the lytic cycle?

A

Viral proteins and replicated DNA are packaged together to form new virus particles (virions) within the host cell.

26
Q

What triggers the release of new virions from the host cell?

A

The accumulation of new virions causes the host cell to become overwhelmed, leading to lysis (bursting) of the cell membrane and releasing the newly formed viruses into the environment.

27
Q

Why do viruses rely on host cells for replication?

A

Viruses lack cellular machinery and metabolic processes; they depend on host cells for energy supply, nutrition, and protein synthesis required for their replication.

28
Q

What distinguishes the lytic cycle from other viral replication cycles, such as the lysogenic cycle?

A

The lytic cycle results in immediate destruction of the host cell, while the lysogenic cycle involves integration of viral DNA into the host genome without immediate lysis, allowing for latent infection.

29
Q

What is an example of a virus that undergoes a lytic cycle?

A

What is an example of a virus that undergoes a lytic cycle?

30
Q

Why is understanding the lytic cycle important in virology?

A

Understanding the lytic cycle provides insights into viral pathogenesis, potential treatment strategies, and how to develop antiviral therapies that target specific stages of viral replication.

31
Q

What is the lysogenic cycle in viruses?

A

The lysogenic cycle is a viral replication process in which a virus integrates its genetic material into the host cell’s genome, allowing it to replicate along with the host cell without causing immediate lysis.

32
Q

How does bacteriophage lambda initiate the lysogenic cycle?

A

Bacteriophage lambda attaches to a bacterial host cell and injects its DNA, which can then integrate into the host’s chromosome.

33
Q

What happens during the integration phase of the lysogenic cycle?

A

The viral DNA, known as a prophage, becomes integrated into the bacterial chromosome, where it can remain dormant and replicate with the host cell’s DNA during cell division.

34
Q

What is a prophage?

A

A prophage is the viral DNA that has been integrated into the host cell’s genome during the lysogenic cycle, remaining inactive until triggered to enter the lytic cycle.

35
Q

How can environmental factors influence the switch from lysogenic to lytic cycle?

A

Environmental stressors, such as UV radiation or certain chemicals, can trigger the prophage to exit the host genome and enter the lytic cycle, leading to active viral replication and cell lysis.

36
Q

What are some consequences of the lysogenic cycle for bacterial populations?

A

The lysogenic cycle can lead to genetic variation in bacterial populations through horizontal gene transfer, as bacteria can acquire new traits from integrated viral DNA.

37
Q

How does lysogeny benefit the virus?

A

By integrating into the host genome, the virus can persist in a dormant state and evade immune responses while ensuring its replication when the host divides.

38
Q

What distinguishes the lysogenic cycle from the lytic cycle?

A

The lysogenic cycle involves integration of viral DNA into the host genome without immediate destruction of the host cell, while the lytic cycle results in rapid replication and lysis of the host cell.

39
Q

Why is understanding the lysogenic cycle important in virology?

A

Understanding the lysogenic cycle provides insights into viral behavior, interactions with host cells, and implications for bacterial evolution and antibiotic resistance.

40
Q

What role do bacteriophages play in microbial ecosystems?

A

Bacteriophages contribute to microbial diversity and population dynamics by influencing bacterial evolution through mechanisms like lysogeny and horizontal gene transfer.

41
Q

What does the diversity of viruses suggest about their origins?

A

The diversity of viruses suggests that they may have originated from multiple sources, possibly evolving from other organisms through various mechanisms.

42
Q

How do viruses exhibit obligate parasitism?

A

Viruses rely entirely on host cells for their survival, obtaining energy, nutrients, and machinery for replication, which reflects an extreme form of parasitism.

43
Q

What is convergent evolution in the context of viral structures?

A

Convergent evolution refers to the development of similar structural features in viruses that arise independently due to similar environmental pressures or functional requirements.

44
Q

How is the genetic code significant in understanding virus origins?

A

The shared genetic code between viruses and living organisms indicates a common evolutionary history, suggesting that some viruses may have evolved from ancestral cellular life forms.

45
Q

What evidence supports the idea that viruses have multiple origins?

A

The presence of similar genetic sequences and structural features across different virus families suggests that viruses may have originated from various hosts and adapted to different environments.

46
Q

How do structural features of viruses relate to their evolutionary origins?

A

Structural features such as capsids and envelopes may have evolved in response to the specific needs of different viral life cycles and host interactions, reflecting their diverse evolutionary paths.

47
Q

What role does horizontal gene transfer play in viral evolution?

A

Horizontal gene transfer allows viruses to acquire genetic material from other organisms, contributing to their diversity and adaptability in various ecological niches.

48
Q

Why is it important to study the origins of viruses?

A

Understanding the origins of viruses can provide insights into their evolution, pathogenicity, and potential strategies for prevention and treatment of viral infections.

49
Q

How do the evolutionary relationships among viruses inform virology research?

A

Studying the evolutionary relationships helps researchers identify potential reservoirs for emerging viruses and understand how they might adapt to new hosts or environments.

50
Q

What implications does the concept of multiple origins have for public health?

A

Recognizing that viruses can originate from various sources emphasizes the need for surveillance and research on diverse organisms to predict and manage potential viral outbreaks effectively.

51
Q

What is meant by rapid evolution in viruses?

A

Rapid evolution refers to the quick genetic changes that occur in viruses, allowing them to adapt swiftly to new environments, host defenses, and treatment strategies.

52
Q

What factors contribute to the rapid rates of evolution in some viruses?

A

Factors include high mutation rates during replication, short generation times, and the ability to exchange genetic material through recombination and reassortment.

53
Q

How does the evolution of influenza viruses exemplify rapid viral evolution?

A

Influenza viruses undergo frequent antigenic drift and shift, resulting in new strains that can evade immune responses and necessitate annual updates to vaccines.

54
Q

What is antigenic drift in influenza viruses?

A

Antigenic drift refers to small, gradual mutations in the virus’s surface proteins (antigens), leading to minor changes that can help the virus escape recognition by the immune system.

55
Q

What is antigenic shift in influenza viruses?

A

Antigenic shift involves a major reassortment of viral genes when two different strains infect the same host cell, resulting in a new subtype that may cause pandemics due to lack of immunity in the population.

56
Q

How does HIV demonstrate rapid evolution?

A

HIV has a high mutation rate due to its reverse transcriptase enzyme, allowing it to quickly adapt to immune responses and antiretroviral treatments.

57
Q

What challenges does the rapid evolution of HIV pose for treatment?

A

The rapid emergence of drug-resistant strains complicates treatment regimens, requiring ongoing adjustments and combination therapies to effectively manage HIV infections.

58
Q

Why is understanding viral evolution important for public health?

A

Understanding how viruses evolve helps inform vaccine development, treatment strategies, and outbreak preparedness, improving responses to emerging viral threats.

59
Q

How does recombination contribute to viral diversity?

A

Recombination allows viruses to exchange genetic material between different strains or species, leading to new variants with potentially enhanced virulence or resistance to treatments.

60
Q

What implications does rapid viral evolution have for vaccine development?

A

Rapid evolution requires continuous monitoring of circulating virus strains and may necessitate frequent updates or modifications to vaccines to ensure efficacy against emerging variants.