Viruses Flashcards

1
Q

Virions

A
  • extracellular phase
  • few or no enzymes
  • not able to reproduce independently of live cells
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2
Q

Viruses

A
  • intracellular phase
  • hijack host cell metabolism to reproduce itself
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3
Q

How do Viruses differ from living cells?

A
  • simple acellular organization
  • either DNA or RNA in virion
  • must reproduce in host
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4
Q

Structural characteristics

A

10nm - 40nm
nucelocapsid covered with capsid

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5
Q

Icosahedral and Helical capsids

A
  • macromolecular
  • protomers
  • associate after replication to form capsid
  • “self-assembly”
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6
Q

Helical and Icosahedral Arrangement

A
  • H: helix around nucleus
  • I: capsomers containing hexamers or pentamers
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7
Q

Viral envelopes

A
  • membrane from host cell
  • proteins coded by viral genes
  • spikes or peplomers
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8
Q

Peplomers function

A

neuraminidase -spikes for penetration
hemagglutinin - spikes bind to RBC

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9
Q

Complex viruses

A

T-Even Coliphages

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10
Q

Proviral DNA

A

genome of a retrovirus after it was intergrated into host chromosome

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