Virus Families Flashcards
1
Q
type of pathogen of virus
A
- obligate intracellular parasite
- can only replicate inside a host cell
2
Q
outside of virus
A
- may be enveloped or naked
3
Q
viral genomes
A
- DNA
- RNA
4
Q
different steps in virus life cycle may provide
A
- targets for antiviral therapy
5
Q
generic virus life cycle
A
- attachment
- entry
- uncoating
- synthesis of protein and nucleic acid
- assembly
- release
6
Q
main components of viruses
A
- protein
- nucleic acids
- lipids
- sugars
7
Q
virion
A
- entire virus particle
8
Q
envelope
A
- may have glycoprotein spike
9
Q
capsid
A
- protein coat surrounding inner part of virus
- basic unit of structure
10
Q
nucleocapsid
A
- protein coat surrounding genome
11
Q
capsomere
A
- subunit
12
Q
envelope derived from
A
- host cell membranes
13
Q
envelope contains
A
- virally encoded proteins that are usually glycoproteins
14
Q
envelope glycoproteins form
A
- spike on surface
15
Q
envelope virus morphology
A
- pleomorphic
- determined by cell of origin
16
Q
functions of capsid proteins
A
- protects viral nucleic acid from environmental stress
- interacts specifically with viral nucleic acid for packaging
- interacts with host receptors for entry to cell
- release of nucleic acid upon entry into new cell
- viral and/or host gene regulation
17
Q
how HIV is unique
A
- nucleocapsid and capsid
18
Q
isocahedral viruses
A
- vast majority
19
Q
isocahedral viruses shape
A
- spherical
20
Q
isocahedral viruses limitation
A
- amount of nucleic acid limited by size of particle
- closed
21
Q
helical virus shape
A
- rod-shaped
22
Q
helical virus limitation
A
- no limit to amount of nucleic acid that can be packaged
- open
23
Q
DNA viruses examples
A
- Poxviridae
- Herpesviridae
- Adenoviridae
- Papovaviridae
- Hepadnaviridae
- Parvoviridae
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