Virus Flashcards
During lytic cycle bacteriophage is known as:
Provirus
influenza virus
-genome of influenza virus is SSRNA
a. Virus: Influenza viruses are enveloped RNA viruses.
b. Epidemic Disease: It is very common in man and occurs in epidemic form.
hepatitis - B
Hepadnaviruses, or hepatitis B viruses (HBVs), are para-retroviruses that harbor a partially double-stranded (ds) DNA genome but replicate this DNA through reverse transcription via an RNA intermediate (the pregenomic RNA or pgRNA)
It is also called serum hepatitis. Hepatitis B (HBV) is the second major form of
hepatitis.
(i) Virus:
Hepatitis B virus (HBV) is a DNA virus.
(ii) Occurrence:
It is very common in Asia, China, Philippines, Africa and the Middle east.
(iii) Transmission:
It is transmitted by the exchange of body fluids, for example blood serum,
breast milk and saliva.
During birth it is transmitted from mother to child.
It is also transmitted by sexual contact.
(iv) Symptoms:
During acute attacks of Hepatitis B different symptoms appear like fatigue,
loss appetite and jaundice.
Infected persons can recover completely and become immune to the virus.
People with chronic hepatitis infection are at the risk of liver damage.
Prevention:
Hepatitis can be controlled by:
Taking hygienic measures, Vaccination. (Genetically engineered vaccine is
available for HBV) and screening of blood/organ/tissue of the donor.
part of virus that is not found in all viruses
envelop
no of capsomeres
- polio virus = 32
2.
arthropod virus are
borne virus
virus was discovered by
iwanovski
absent in virus
energy liberation
diarrhea caused by
DSRNA
cancer caused by
rous sarcoma
DNA containing plant virus
cauliflower virus
tobacco mosaic virus
- rod shaped
the first one to isolate plant virus in crystalline form
stanley (1935)
Size of virus from smallest to largest
Small= poxvirus=250nm
Large= parvovirus= 20nm
Capsomeres no
- herpes virus= 162
- Adenovirus= 252
- polio virus= 32
Shapes of Bacteriophages:
These have two shapes (structural forms):
1. Cubical: These arc regular solid or icosahedral (having 20 triangular faces).
2. Helical Symmetry: They are rod shaped. Many phages consist of head and tail.
The heads are polyhedral but tails are rod shaped.
Structure of Bacteriophage
Bacteriophage meaning bacteria eater, earlier workers studied few phages
that infect Escherichia coli. Of these the best phages are T phages (T for type).
Two main types of T phages are T2 and T4.
Structure of T4:
The structure under electron microscope looks like a tadpole and consists of
head and tail.
1. Head: The head is elongated having Pyramidal (having two triangular
structures with common. base), hexagonal or prism shaped structure to it
straight tail is attached. Head contains double stranded DNA.
2. Tail: The structure of tail is more complex than head. Tail has a core of protein
which is surrounded by a sheath of another protein. On one side of the sheath is collar and on the other side is end plate (Base plate). Six tail fibers are
attached to the end plate. These fibers are for attachment.