Virulence factors Flashcards

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1
Q

Actinobacillus (4)

A
  • Capsule
  • Exotoxin
  • Cytotoxin
  • Fimbriae
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2
Q

Escherichia Coli (7)

A
  • Capsular K antigen
  • Endotoxin (Lipid A)
  • Fimbriae
  • Hemolysins
  • Siderophores
  • Enterotoxins
  • Vero Toxin
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3
Q

Capsular K antigen

E. Coli strains

A
  • Prevention agains the immune system
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4
Q

Endotoxin (Lipid A)

E. Coli strains

A
  • Part of the Cell Wall
  • Released after Lysis of Bacterial cell
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5
Q

Fimbriae

E. Coli stains

A
  • Adherent antigens
  • Enable Bacteria to attach to the surface of Enterocytes
  • Colonising in the Small Intestines
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6
Q

Hemolysins

E. Coli stains

A
  • Damage the host cell membrane
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7
Q

Siderophores

E. Coli strains

A
  • Binds iron
  • Absolute requirement for growth of E. Coli strains
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8
Q

Enterotoxins

E. Coli strains

A
  • ST (Heat stable toxin)
  • LT (Heat labile toxin)
  • Disturbe Osmolality Balance
  • Induce Hyper-Secretion into intestines
  • Diarrhea
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9
Q

Vero Toxin

E. Coli strains

A
  • Damage Enterocytes and Blood vessels
  • Causes Oedema disease in pigs
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10
Q

Salmonella

A

Lipopolysaccharides
* Adherent antigens
* Somatic O antigen
* Endotoxins

Exotoxins
* Enterotoxin
* Cytotoxin

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11
Q

Adherent Antigens

Salmonella

A
  • Colonisation and adheres to the surface of Intestinal Mucosal Cells

ATH same ase Fimbriae

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12
Q

Somatic O antigen

Salmonella

A
  • Resistance to Digestion by Phagocytes
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13
Q

Endotoxins

Salmonella

A
  • Damage Intestinal Mucosa
  • Responsible for Haemorrhage and Perforation
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14
Q

Enterotoxin

Salmonella

A
  • Similar affect to LT toxin of E. Coli
  • Hypersecretion of fluid and electrolytes into intestines = Diarrhaea
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15
Q

Cytotoxin

Salmonella

A
  • Same asShigela-Like toxin
  • Inhibits the synthesis of proteins of Intestinal epithelial cells
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16
Q

Klebsiella (1)

A

Main virylence facor:
* Produce a Capsule

17
Q

Proteus (3)

A
  • Urease activity
  • Proteolytic activity
  • Adherent Fimbriae
18
Q

Bibersteinaia (4)

Genus

A
  • Fimbriae = Attachment to mucous membrane
  • Capsule = Protection agains Phagocytosis
  • Endotoxin = Tissue and Endothelial damage
  • Exotoxins = Dermonecrotoxin, Cytotoxin and Lethal toxin