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Microbiology > Virology Random facts > Flashcards

Virology Random facts Flashcards

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Biology 101 flashcards
1
Q

Orthomyxoviridae species…

A

Influenza

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2
Q

Paramyxoviridae species…

A

Morbillivirus:Measles
Parymyxovirus: Mumps
Parinfluenza
Pneumovirus: Human Respiratory Syncytial Virus (RSV)

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3
Q

Cause of SARS

A

Coronavirus

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4
Q

Cause of croup

A

Adenovirus, influenza, and parainfluenza

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5
Q

Outbreaks in Bone marrow transplant wards

A

Adenovirus

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6
Q

Adenovirus serotypes commonly associated with outbreaks

A

3, 7a, 7b, 14 and 19

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7
Q

Smallest DNA virus

A

Parvoviruses

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8
Q

Needs a helper virus to grow in mitotically active cells

A

Adeno associated Virus

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9
Q

Picornavirus that doesn’t replicate in GI tract

A

Rhinovirus

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10
Q

Picrornavirus species…

A

Enterovirus: polio, Coxsackievirus, Echovirus
Rhinovirus
Hepatovirus-Hepatitis A virus

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11
Q

Polyprotein made by one large open reading frame

A

Poliovirus

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12
Q

No viral enzymes required for translation of viral RNA

A

Poliovirus

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13
Q

Hand foot and mouth disease

A

Coxsackievirus group A 16

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14
Q

Cruise Ship outbreaks

A

Norwalk virus

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15
Q

Leading cause of food-borne outbreaks in US

A

Norwalk virus

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16
Q

dsRNA virus

A

Rotavirus

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17
Q

Double layer capsids

A

Rotavirus (Unique?)

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18
Q

NSP4 protein

A

Rotavirus, Cholera toxin activity

Prevents water reabsorption

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19
Q

DNA Hepatitis

A

Hepatitis B

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20
Q

Picornavirus Hepatitis

A

Hepatitis A

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21
Q

Flavivirus Hepatitis

A

Hepatitis C and G

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22
Q

Hepadnavirus Hepatitis

A

Hepatitis B

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23
Q

HBsAG

A

Hepatitis B surface Ag

Diagnositic for acute hepatitis B

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24
Q

Anti-HBs

A

Antibody to HBsAg

Diagnostic for acute hepatitis B

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25
Q

Anti-HBc

A

Antibody to HBcAg in acute and chronic carriers
IgM=Acute
IgG=Chronic

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26
Q

Cause of hepatocellular carcinoma

A

Hepatitis C

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27
Q

6 Classic Childhood Exanthems

A 
1-Measles
2-Strep
3-Rubella
4-Extinct
5-Parvovirus B19
6-HHV 6 and HHV 7
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28
Q

Photophobia

A

Measles

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29
Q

Koplik’s Spots

A

White spots on Buccal and lower labial mucosa opposite the lower molars
Measles

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30
Q

Microscopy of multinuecleated giant cells in nasopharyngeal secretions

A

Measles

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31
Q

Togavirus

A

Rubella

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32
Q

TORCHES

A 
Taxoplasma Gondii
Rubella
Cytomegalogvirus
Herpes and HIV 
Syphillis
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33
Q

Thrombocyopenic purpura-blueberrymuffin

A

RUBELLA

measles

34
Q

Only infect mitotically active cells

A

Parvovirus B19

35
Q

Face-slap disease

A

Parvovirus B19

36
Q

Hydrops fetalis

A

Parvovirus crossing placenta

37
Q

Break bone fever

A

Dengue fever

38
Q

Bullet shaped

A

Rhabdovirus (Rabies)

39
Q

Hydrophobia

A

Rabies

40
Q

Negri Bodies

A

Rabies

41
Q

Sin Nombre

A

North American Hantavirus with deer mouse resevoir

42
Q

Only DNA that replicates entirely in host cytoplasm

A

Poxivirdiae (smallpox)

43
Q

Lentivirinae species

A

HIV

44
Q

Deltaretrovirus

A

Human T-lymphotropic virus

45
Q

HIV gag gene

A

Matrix proteins-structural

46
Q

HIV pol gene

A

Protease, RT and Intergrase

47
Q

HIV Env gene

A

Surface glycoprotein

48
Q

Tegument matrix

A

Herpes

49
Q

HHV-1

A

Herpes simplex virus 1
Mucoepithelial cells
Oral
Latency in nerve ganglia

50
Q

HHV-2

A

Herpes simplex virus 2
Sexual
Genital
Latency in nerve ganglia

51
Q

HHV-4

A

Epstein Barr virus
Kissing
Mono and lymphoma
Latency in B lymphocytes

52
Q

HHV-5

A

Cytomeglovirus
Congenital and Sexual transmission
Mono
Monocytes, neutrophils, vascular endothelial cells latency

53
Q

HHV-6

A

Human herpesvirus 6
Roseola in infants
Latency in T lymphocytes, monocytes and macrophages

54
Q

HHV-8

A

Kaposi sarcoma associated herpesvirus
Tumors
Latency virus infected tumors

55
Q

Heparin sulfate

A

Herpes binds to enter cell

56
Q

VP16 tegument protein

A

virus encoded trasncripion activation factor used by Herpes

57
Q

Ballooning of cells in viral culture

A

Herpes

58
Q

Multinucelated giant cellls with Toluidine blue and Cowdry type A inclusions

A

Herpes (Tzanck Smear)

59
Q

Gamma herpes virus

A

Epstein Barr Virus

60
Q

Use complement component CR2 and CD21

A

Epstein Barr virus

61
Q

Atypical Lymphocytes

A

Epstein Barr Virus

62
Q

EBNA IgG

A

Lifelong marker for primary infection of Epstein Barr Virus

63
Q

Beta Herpes virus

A

Cytomegalovirus

64
Q

Owl’s eye-Histopatology of lung

A

Cytomegalovirus

65
Q

Rb protein

A

Inhibits cell entry into G1/S phase

66
Q

P53

A

Induces cell cycle arrest or apoptosis

67
Q

HPV 16 and 18

A

Squamous cell carcinoma of cervix

68
Q

HPV 6 and 11

A

Benign cervical warts

69
Q

E6

A

Binds to p53 targets degradation

70
Q

E7

A

Binds to Rb prevents from inhibiting proliferation

71
Q

Pap Smear for….

A

HPV- perinuclear vacuolated cytoplasm

72
Q

EBNA 1

A

Maintains presence of viral genome

73
Q

EBNA 2

A

Stimulates B cell proliferation

74
Q

EBNA 3

A

Inactivates Rb, stimulates cell gene expression

75
Q

Late membrane proteins

A

Stimulate proliferation

76
Q

Tax gene

A

Activates cellular genes encoding T cell growth factors (HTLV-1)

77
Q

Virion consists of…

A

Nucleic acid genome, protein capsid, spike. +/- regulatory proteins, +/- lipid envelope

78
Q

Eclipse phase

A

no infectious particles

79
Q

Latent phase

A

no infectious particles outside of host cell

80
Q

Parvorvirus Replication strategy

A

single stranded DNA must be converted to double stranded before it can be transcribed

81
Q

Poxvirus Replication strategy

A

replicate in the cytoplasm

Must encode all of the proteins needed for gene expression and replication

82
Q

Two RNA viruses that do not replicate in cytoplasm

A

Orthomyxoviruses and Retroviruses

Microbiology (10 decks)

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