Symptoms of Bacteria infection Flashcards
Corynebacterium Diptheriae
Inflammation of respiratory epithelium
Fever, sore throat, malaise
Systemic–> acute myocarditis and nerve cells
Clostridium tetani
Spastic paralysis
lockjaw
Opisthotonos
Clostridium botulinum
Slurred speech difficulty swallowing double/blurred vision Dilated pupils and drooping eyelids muscle weakness NO FEVER Floppy baby syndrome-lethargy, constipation, weak cry, difficulty feeding Therapeutic-involuntary muscle contractions, excessive sweating disorders, treatment of migraines Cosmetic removal of wrinkles
Vibrio Cholerae
Rice water stools
copious watery diarrhea
no inflammation
Impetigo (Staph)
caused by toxin
localized blisters-culture +
Toxic Shock Syndrome (Staph)
no bacteremia
supertoxin systemic
fever, macular rash, hypotension, desquamation, diarrhea, vomiting, sore throat, muscle pain, pupura fulminans
Scalded Skin Syndrome (Staph)
Caused by exfoliating toxin
cutaneous blisters cover the body
desquamation of epithelium
recovery folowing Ab formation
Food poisoning (Staph)
Ingestion of organs not needed just enterotoxin
Rapid diarrhea, vomiting and nausea
NO FEVER
Systemic Staph infections
Osteomyelitis and septic arthritis
endocarditis
pneumonia
empyema
Skin and wound infections (Strep)
Impetigo erysipelas Cellulitis necrotizing fasciitis puerperal fever
Strep Throat
localized epthelial damage
Scarlet fever
erythrogenic toxin produced
red cheeks
strawberry tongue
Toxic shock-like syndrome
pyrogenic exotoxin
bacteria are systemic
Rheumatic fever
Ab to bacteria cross reacts with heart tissue
Inflammation of heart, joints and blood vessels
chronic progressive damage
glomerulonephritis
accumulation of immune complexes in kidneys
acute inflammation of renal gomeruli
blood, protein in urine, edema, hypertension
Streptococcus pneumoniae
Bloody sputum
Chest pain
Legionnaires disease
necrotizing of alveoli and terminal bronchioles
myalgia, headache, fever, dry cough, chills, chest pain
multiorgan involvement (liver)
Shock, respiratory failure
Pontiac fever
self limiting
fever, chills, headache, myalgia
resolves within 2-5 days
Mycobacterium tuberculosis
Primary-Ghon complex
Granulomas form
Secondary: chronic fever, weight lsos, night sweats, bloody sputum, extesive tissue damage
Extensive caseous necrosis of lung
Chlamydia trachomatis
Men: urethritis
Women: vagintitis/cervicitis/ PID
Asymptomatic
lead to infertitlity or ectopic pregnancy
Lymphogranuloma venereum-inflammation of lymph node–> painful buboes
Trachoma -discharge of eyes
Reiter’s syndrome
Chlamydia
joints, urethra, eyes and skin
Neisseria gonorrhoeae
Men: urethritis
Women: vaginitis/cervicitis
PID salpingitsi
Pharyngitis, conjuctivitis, disseminated infection
Neisseria meningitidis
fever, petechial skin rash, thrombocytopenia,
Disseminated intravascular coagulation–> endotoxic shock destruction of adrenal glands
Treponema pallidum
Primary: syphilitic chancre
Secondary: skin eruptions
condylomata lata-mucosal warty erosions
Tertiary: chronic inflammation damage to organs gummas form in bones and joints
Neurosyphilis can occur at any stage: bacteria invade brain
Lyme disease
Stage 1: erythema migrans (bulls eye rash)
Stage 2: disseminated rash, inflammation, fatigue, chills, fever, headache, muscle joint ache, swollen lymph nodes, cardiac dysfunction and neurological signs
Stage 3: chronic phase
arthritis, cross reaction between OMPs and human Ag–> autoimmunity
Shigella
Erosions or ulcers in the gut walls–> inflammatory colitis and bloody dysentery
Gastroenteritis
nasusea, vomiting, diarrhea, muscle ache and cramping, bacteremia rare
Typhoid fever
fever, headache, fatigue, myalgia,
bacteria systemic
ETEC
cholera-like diarrhea
EIEC
watery to dysentery diarrhea
EPEC
Watery diarrhea
EHEC
hemorrhagic colits
UPEC
UTIs
SEC
neonatal sepsis and meningitis