Parasite and Fungi fun facts Flashcards
Latex agglutination for antigen
Cryptococcosis
Complement fixation or immunodiffusion for antibody
coccidiodomycosis
enzyme immunoassay for antigen
Histoplasmosis
EIA for galactomannan Ag
Aspergillosis
nephrotoxicity
Amphotericin B
changes in light perception
voriconazole
Binds to ergosterol
Polyenes (amphotericin)
Inhibits lanosterol 14alpha-demethlyase cytochrome P-450 dependent enzymes
Azoles
blocks synthesis of beta-1.3-dglucan effective for aspergillus and candida
Echinocandins-__________fungin
5-FC deaminated to 5-Fu inhibition of DNA and RNA synthesis
Antimetabolites-flucytosine
Wood lamp-yellow
Pityriasis/Tinea Versicolor- Malassezia furfur
olive oil culture with spaghetti and meatballs as result
pityriasis/tinea versicolor-malassezia furfur
whitfield ointment
Tinea nigra
Positive hair perforation
Trichophyton mentagrophytes
negative hair perforation
Trichophyton rubrum
daisy petal culture
Lymphocutaneous sporotrichosis-sporothrix schenckii
copper pennies culture
chromoblastomycosis-cladosporium, fonsecaea pedrosoi
Squamous cell carcinoma differential diagnosis
chrmoblastomycosis-cladosporium, fonsecaea pedrosoi
serosanguineous fluid with visible granules from sinus tracts
eumycotic mycetoma
surgical excision of cyst for diagnosis
Subcutaneous phaeohyphomycosis
Fontana-Masson stain for melanin
Subcutaneous phaeohyphomycosis
spherules in alveoli
Coccidiodomycosis
barrel shaped arthroconidia
Coccidiodomycosis
Only in California
Coccidiodomycosis immitis
Coin lesion
Blastomycosis, histoplasmosis, coccidiodomycosis
Mariener’s wheel
Paracoccidiodomycosis
serologic testing in blood and urine
Histoplasmosis
Mechanical barrier interuption-catheters, heart valves, pacemakers, prosthetic joints
Candidiasis
Grunulocyte dysfunction-Chemotherapy, bone marrow transplant
Aspergillosis, Zygomycosis, Candidiasis
depressed cell mediated immunity-Steroid therapy, organ tranpslant, AIDS
Candidiasis, coccidiolmycosis, cryptococcocis, histoplasmosis, pneumocystosis
Phenotypic switching
Candididiasis
normal microflora
candidiasis
CHROMagar
candidiasis
Birdseed/niger seed agar
Cryptococcosis
Bathroom
Rodotorula
Acute angle hyphae
Aspergillosis
Ninety degree angle hyphae
zygomycosis
Resistance to voriconazole
Zygomycosis
Lid lifter
zygomycosis-mucor
White forward/black reverse Sabouraud plate
Philophora verrucosa
black foward/white reverse sabouraud plate
Aspergillus niger
No budding
Pneumocystosis
2 serum tests IgM first then IgG
Toxoplasma gondii
newborn just IgM
atovaquone
toxoplasma gondii
high in Michigan
Cryptosporidium, Giardia lamblia
AIDS indicator
Cryptosporidium
Acid fast stain
Cryptosporidium
flask shaped ulcer
entamoeba histolytica
improper contact handling
ancathamoeba
exists only as a trophozoite
trichomonas vaginalis
microscopic examination has to be wet and warm
trichomonas vaginalis
Smiley face with mustache
giardia lamblia
Smiley face w/o mustache
trichomonas vaginalis
sandfly
leishmania donovani
high IgG–> glomerulonephritis
Leishmania donovani
Tsetse fly
trypanosoma brucei
Massive B cell activation (IgM)
trypanosoma brucei
highly variable surface glycoprotein that is switched to avoid immune response in blood
trypanosoma brucei
Kissing bug/triatomid/reduvidd bug
trypanosoma cruzi
prefer tissues of mesenchymal origin
trypanosoma cruzi
rats, cats and dogs are definitive hosts
trypanosoma cruzi
loss of parasympathetic and cardiac intrinsic signaling
trypanosoma cruzi
hyperinfection
strongyloids stercoralis
infective larvae in stool very infective health care workers
strongyloides stercoralis
no eggs in stool because no adult worms
toxarcar canis- dog roundworm
no egg laying
trichinella spiralis
Thin skin snips diagnosis
Onchocera
pseudotubercles (white granulomas) in liver
schistosoma
criss cross burrowing tracks
mites