Virology (Middleton)

Question 1

Which viruses contain (-)ssRNA?

Answer 1

1. Measles virus
2. Respiratory Syncytial Virus
3. Rabies virus
4. Influenza virus

Question 2

What viruses contain dsDNA?

Answer 2

1. Varicella Zoster virus
2. Rotavirus
3. Hep B
4. Adenovirus
5. Herpes Simplex
6. HPV

Question 3

What viruses contain (+)ssRNA?

Answer 3

1. Poliovirus
2. Hep C
3. EEE and VEE
4. West Nile Virus
5. HLTV-1
6. HIV

Question 4

Which viruses are non-enveloped?

Answer 4

1. Poliovirus
2. Rotavirus
3. Adenovirus
4. HPV

Question 5

What special proteins are involved with (-)ssRNA?

Answer 5

Must have an RNA POLYMERASE to make + sense RNA to make proteins

Question 6

What special protein is involved with poliovirus?

Answer 6

Capsid proteins

Question 7

What special protein is involved with Hep B?

Answer 7

Reverse transcriptase

Question 8

What viruses have a reverse transcriptase that converts RNA -> DNA?

Answer 8

1. Hep B

2. Retroviruses (HLTV-1 and HIV)

Question 9

What are the special proteins involved with the influenza virus?

Answer 9

1. Hemagglutinin (HA): cell attachment

2. Neuraminidase (NA): cell budding

Question 10

Which virus has an extremely large genome?

Answer 10

Varicella Zoster virus

Question 11

Which virus has a very small genome?

Answer 11

Hep B

Question 12

What is special about the (+)ssRNA in retroviruses?

Answer 12

They have diploid identical copies

Question 13

What is special about the HPV dsDNA?

Answer 13

It is circular DNA

Question 14

Which viruses enter via membrane fusion?

Answer 14

1. Measles
2. Respiratory syncytial virus
3. Retroviruses (HLTV-1 and HIV)

Question 15

How does the influenza virus enter the cell?

Answer 15

Cell attachment with HA -> confirmation change -> entrance

Question 16

Which viruses replicate in the nucleus?

Answer 16

1. Varicella Zoster
2. Hep B
3. Influenza
4. Adenovirus

Question 17

What is special about the processing of the genome of retroviruses?

Answer 17

Reverse transcriptase of RNA to DNA in cytoplasm -> migrates to nucleus for replication

Question 18

Which viruses have multiple phases of transcription?

Answer 18

1. Varicella zoster

2. Adenovirus

Question 19

T/F: Hep B uses an RNA intermediate to replicate DNA.

Answer 19

TRUE

Question 20

Which virus lyses the cell to release?

Answer 20

Poliovirus

Question 21

Which diseases have long incubation periods?

Answer 21

1. Hep B
2. Hep C
3. Rabies
4. HLTV-1
5. HIV
6. HPV

Question 22

Which virus causes most warts?

Answer 22

HPV

Question 23

What virus uses CAR to enter the cell?

Answer 23

Adenovirus

Question 24

Which virus starts as (+)ssRNA then uses a DNA intermediate and integrates to into the host DNA?

Answer 24

Retrovirus (HIV and HLTV-1)

Question 25

What is special about Hep B replication?

Answer 25

It uses an RNA intermediate

Question 26

What are the repeating protein subunits that create a protein capsid?

Answer 26

Capsomeres

Question 27

What is an envelope made of?

Answer 27

Lipid-bilayer

Question 28

Which type of genome requires a polymerase to make (+)ssRNA?

Answer 28

(-)ssRNA

Question 29

What do all viruses need from the host cell to produce proteins?

Answer 29

RIbosomes

Question 30

What types of genomes must gain access to the nucleus?

Answer 30

ssDNA and dsDNA

Question 31

What types of cells use budding to release?

Answer 31

Enveloped