Virology Flashcards
All DNA viruses have linear DNA except
Papilloma Polyoma Hepadna
All DNA viruses have double-stranded DNA EXCEPT
Parvovirus
All DNA viruses are icosahedral EXCEPT
Poxvirus
All DNA viruses replicate in the nucleus EXCEPT
Paxvirus
Mode of transmission: respiratory and transplacental Not oncogenic No vaccine
Parvovirus B19
Only virus with fiber
Adenovirus
Mode of transmission: respiratory and fecal-oral Not oncogenic Has a vaccine against it
Adenovirus
Mode of transmission: sexual and skin contact Oncogenic Has a vaccine against it
Human Papilloma
What encodes for proteins that inactivate tumor suppressor genes
Genes E6 and E7
Cultured in shell tubes Negative heterophil test
Cytomegalovirus (CMV)
Most common cause of congenital abnormalities
CMV
Most common cause of blindness in AIDS patients
CMV
Only DNA virus that produces DNA by reverse transcription with mRNA as the template
Hepatitis B
What virus has 1) Guarneri bodies 2) Henderson-Peterson bodies
1) Smallpox 2) Molluscum contagiosum Both have Intracytoplasmic eosinophilic inclusions
Downey cell Burkitt’s lymphoma Kissing disease
EBV
+ HBsAg - Anti-HBs - Anti-HBc + HBeAg
Incubation Period Hep B
+ HBsAg - Anti-HBs + Anti-HBc (+IgM) + HBeAg
Acute Hep B infection
- HBsAg - Anti-HBs + Anti-HBc (+IgM) - HBeAg
Window Period Hep B
- HBsAg + Anti-HBs + Anti-HBc (+IgG) - HBeAg
Complete Recovery Hep B
+ HBsAg - Anti-HBs + Anti-HBc (+IgG) - HBeAg
Chronic carrier Hep B
+ HBsAg - Anti-HBs + Anti-HBc (+IgG) + HBeAg
Chronic Active Hep B
- HBsAg + Anti-HBs - Anti-HBc - HBeAg
Vaccinated against Hep B
Where is the site of latency of 1) HSV 1 2) HSV 2
1) trigeminal ganglia 2) lumbosacral ganglia
Large, pink to purple intranuclear inclusions (Cowdry type A) Multinucleated giant cells on Tzanck smear
Herpes Simplex Virus
All RNA viruses have single-stranded DNA except
Reovirus Rotavirus Colorado Tick Fever
All RNA viruses replicate in the cytoplasm except
Influenza Retrovirus
Virus that replicates in the anterior horn of the spinal cord causing paralysis
Poliomyelitis
Viruses that have Cowdry type B intranuclear inclusions
Poliomyelitis Adenovirus
Most common cause of viral myocarditis and pericarditis
Coxsackie Virus (specifically type B)
Most common cause of aseptic meningitis
ENTEROVIRUSES coxsackie polio echo
Also known as Enterovirus 72
Hepatitis A
Most common cause of nonbacterial diarrhea in adults
Norwalk virus (Norovirus)
Most common cause of childhood diarrhea
Rotavirus
Has major antigens hemagglutinin (H) and neuraminidase (N)
Influenza virus
Most common cause of respiratory tract infection
Influenza virus (specifically type A)
Examples of Paramyxoviridae virus
Parainfluenza Virus RSV Measles Virus Mumps Virus
Pathognomonic enanthem of Measles
Koplik’s spots
Cardinal manifestations of measles
Cough Coryza Conjunctivitis Koplik spots
+ Hemagglutinin - Neuraminidase + Fusion protein
Measles
+ Hemagglutinin + Neuraminidase + Fusion protein
Mumps and Parainfluenza
- Hemagglutinin - Neuraminidase + Fusion protein
Respiratory Syncitial Virus
Treatment for RSV
Ribavirin but since we don’t have it in the Philippines, supportive treatment.
Most prevalent of the AIDS defining illnesses
42.6% P. carinii penumonia 15.0% Esophageal candidiasis 10.7% Wasting 10.7% Kaposi’s sarcoma 4.8% Disseminated MAC
Name the abnormalities associated with Congenital Rubella Syndrome
PDA Congenital cataracts Sensorineural deafness Mental retardation Blueberry muffin baby
