Mycology

Question 0

Substance in fungal cell wall

Answer 0

Chitin

Question 1

Character of fungi: true nucleus, 80s ribosomes, mitochondria

Answer 1

Eukaryotic

Question 2

Major membrane sterol of fungi

Answer 2

Ergosterol

Question 3

Inhibit ergosterol synthesis

Answer 3

Imidazole antifungals

Question 4

Bind more tightly to ergosterol than cholesterol

Answer 4

Polyene antifungals

Question 5

Organisms living on dead organic material

Answer 5

Saprophytic or saprobic

Question 6

Two basic forms of fungal structure

Answer 6

Yeast Mold

Question 7

Basic forms of fungal structure exhibit this character

Answer 7

Thermal dimorphism

Question 8

Two type of host response of fungal pathogens

Answer 8

Granulomatous response Pyogenic response

Question 9

Fungal toxin in Amanita mushroom that causes liver necrosis

Answer 9

Amanitin Phylloidin

Question 10

Ingestion of contaminated peanuts and grains causes liver cancer due to

Answer 10

Aflatoxin (Aspergillus flavus toxin)

Question 11

Laboratory diagnosis of fungi that uses low pH to inhibit the growth of bacteria

Answer 11

Sabouraud’s agar

Question 12

Infect only superficial keratinized structures Septate hyphae in 10% KOH Hyphae and conidia on Sabouraud’s agar Green fluorecence on Wood’s lamp

Answer 12

Dermatophytoses

Question 13

Three important dermatophytes

Answer 13

Microsporum canis Trichophyton tonsurans Epidermophyton floccosum

Question 14

Asteroid body Dimorphic fungi that lives on vegetation Occurs most often in gardeners via thorn prick

Answer 14

Sporotrichosis

Question 15

Dimorphic fungus that exists as mold in soil and yeast in tissue/spherules Inhaled by arthrospores Treated with amphotericin B or itraconazole

Answer 15

Coccidioides immitis

Question 16

Influenza-like illness Lung infiltrates, adenopathy, effusions Erythema nodosum Arthralgias Meningitis

Answer 16

Valley fever

Question 17

Two great mimickers of PTB

Answer 17

Histoplasmosis Paragonimus

Question 18

Two types of of asexual spores formed by Histoplasma capsulatum

Answer 18

Tuberculate macroconidia Microconidia

Question 19

Round yeast with broad-base bud Transmitted by inhalation of conidia Most common cause of fungal pneumonia Ulcerated granulomas Lytic bone lesions Prostatitis

Answer 19

Blastomyces dermatitidis

Question 20

Thick yeast with multiple buds in wheel configuration (mariner’s wheel) Transmitted via inhalation of conidia Chronic pneumonia with painful ulcers on mouth and nose

Answer 20

Paracoccidioides brasiliensis

Question 21

Predisposing factors to opportunistic mycosis

Answer 21

Broad-spectrum antibiotic use Steroid use Hematologic malignancies Transplant recipients Systemic chemotherapy AIDS

Question 22

Normal flora of URT, GIT, FGUT May appear as oval yeast with a single bud or as pseudohyphae Form germ tubes in serum and chlamydo-spores in culture

Answer 22

Candida Albicans

Question 23

Presentation of Candida albicans in immunocompromised patients

Answer 23

Pseudomembranous esophagitis Subcutaneous nodules Right-sided endocarditis

Question 24

Diagnostic tests that show the presence of Cryptococcus neoformans

Answer 24

Oval yeast with narrow-based bud surrounded by a wide polysacchtadise capsule seen in India ink preparation Positive latex agglutination test

Question 25

Grows abundant in soil with bird droppings Transmission by inhalation of airborne yeast cell (Eucalyptus tree) Asymptomatic lung infection, meningitis, encephalitis

Answer 25

Cryptococcus neoformans

Question 26

Exists as molds, with septate hyphae that form V-shaped dichotomous branches

Answer 26

Aspergillus fumigatus

Question 27

Asthmatic symptoms with expectoration of brownish bronchial pulgs

Answer 27

Allergic bronchopulmonary aspergillosis

Question 28

Saprophytic mold with non-septate hyphae with walls and branches at right angles Rhino-orbital-cerebral infectionnwith eschar formation Common in patients with DKA, burns, leukemia

Answer 28

Rhizopus oryzae / Mucormycosis

Question 29

An indeterminate organism that is diagnosed by staining BAL washings Transmission is by inhalation of cysts Cysts in the alveoli induce an inflammatory response consisting plasma cells Seen in diffuse interstitial pneumonia with ground glass infiltrates bilaterally

Answer 29

Pneumocystis jiroveci

Question 30

Major surface glycoproteinnof Pneumocystis jiroveci undergoes \_\_\_\_\_

Answer 30

Programmed rearrangements

Question 31

Inciting organism of Tinea Versicolor Spaghetti and meatballs appearance on 10% KOH

Answer 31

Malassezia Furfur