Mycology Flashcards
Substance in fungal cell wall
Chitin
Character of fungi: true nucleus, 80s ribosomes, mitochondria
Eukaryotic
Major membrane sterol of fungi
Ergosterol
Inhibit ergosterol synthesis
Imidazole antifungals
Bind more tightly to ergosterol than cholesterol
Polyene antifungals
Organisms living on dead organic material
Saprophytic or saprobic
Two basic forms of fungal structure
Yeast Mold
Basic forms of fungal structure exhibit this character
Thermal dimorphism
Two type of host response of fungal pathogens
Granulomatous response Pyogenic response
Fungal toxin in Amanita mushroom that causes liver necrosis
Amanitin Phylloidin
Ingestion of contaminated peanuts and grains causes liver cancer due to
Aflatoxin (Aspergillus flavus toxin)
Laboratory diagnosis of fungi that uses low pH to inhibit the growth of bacteria
Sabouraud’s agar
Infect only superficial keratinized structures Septate hyphae in 10% KOH Hyphae and conidia on Sabouraud’s agar Green fluorecence on Wood’s lamp
Dermatophytoses
Three important dermatophytes
Microsporum canis Trichophyton tonsurans Epidermophyton floccosum
Asteroid body Dimorphic fungi that lives on vegetation Occurs most often in gardeners via thorn prick
Sporotrichosis