Virology Flashcards
Most viral DNA genomes are
double stranded, linear
Most viral RNA genomes are
single stranded, linear
Positive sense vs negative sense RNA viruses?
+ss, A type of viral RNA that, unlike negative-sense RNA, can be readily translated into proteins.
negative sense RNA viruses need?
-ss must be transcribed by RNA-dependent RNA polymerase into positive-sense RNA before it can be translated into proteins.
Enveloped vs non-enveloped viruses in terms of capsid
Enveloped: Helical capsid structure
Icosahedral capsid structure in both non-enveloped viruses and enveloped viruses
What is the envelope?
Lipid bilayer around the capsid that contains viral glycoproteins and host cell proteins
Nonenveloped viruses are often environmentally resistant.
The presence of the lipid bilayer makes nearly all enveloped viruses vulnerable to rapid inactivation by organic solvents (e.g., alcohol), detergents, and dry heat