Virology Flashcards

1
Q

Most viral DNA genomes are

A

double stranded, linear

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2
Q

Most viral RNA genomes are

A

single stranded, linear

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3
Q

Positive sense vs negative sense RNA viruses?

A

+ss, A type of viral RNA that, unlike negative-sense RNA, can be readily translated into proteins.

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4
Q

negative sense RNA viruses need?

A

-ss must be transcribed by RNA-dependent RNA polymerase into positive-sense RNA before it can be translated into proteins.

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5
Q

Enveloped vs non-enveloped viruses in terms of capsid

A

Enveloped: Helical capsid structure

Icosahedral capsid structure in both non-enveloped viruses and enveloped viruses

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6
Q

What is the envelope?

A

Lipid bilayer around the capsid that contains viral glycoproteins and host cell proteins

Nonenveloped viruses are often environmentally resistant.

The presence of the lipid bilayer makes nearly all enveloped viruses vulnerable to rapid inactivation by organic solvents (e.g., alcohol), detergents, and dry heat

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